The correlation between vaginal microecological dysbiosis-related diseases and preterm birth: A review

• Main Authors: Yuan Gao, Qingyao Shang, Jing Wei, Tingtao Chen
• Format: Article
• Language: English
• Published: Elsevier 2021-06-01
• Series: Medicine in Microecology
• Subjects: Vaginal microecology; Vaginal microecological dysbiosis; Preterm birth; Microbial therapy
• Online Access: http://www.sciencedirect.com/science/article/pii/S2590097821000112

In the 21st century, the incidence of preterm birth has continued to increase. According to statistics, preterm birth accounts for 5%–18% of all births worldwide, and 70%–75% of perinatal deaths are related to preterm birth. Preterm birth is not only a cardiopulmonary defect for the baby, but also has a negative impact on the mother's health. Many studies have shown that vaginal microecological dysbiosis-related diseases are the most common causes of preterm birth, such as bacterial vaginosis (BV), vulvovaginal candidiasis (VVC), group B streptococcal (GBS) infections and other infectious diseases. Therefore, we have a review of the deeper understanding of the links and mechanisms between vaginal microecological dysbiosis-related diseases and preterm birth. In addition, timely restoration of vaginal microecology through microbial therapy become the key to prevent and reduce the incidence of preterm birth.