The First Dose of Fingolimod Affects Circulating Extracellular Vesicles in Multiple Sclerosis Patients

The First Dose of Fingolimod Affects Circulating Extracellular Vesicles in Multiple Sclerosis Patients

Extracellular vesicles (EVs) are membrane-bound particles involved in intercellular communication. They carry proteins, lipids, and nucleotides such as microRNAs (miRNAs) from the secreting cell that can modulate target cells. We and others have previously described the presence of EVs in peripheral...

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Bibliographic Details
Main Authors: Matías Sáenz-Cuesta, Ainhoa Alberro, Maider Muñoz-Culla, Iñaki Osorio-Querejeta, Marta Fernandez-Mercado, Itziar Lopetegui, Mikel Tainta, Álvaro Prada, Tamara Castillo-Triviño, Juan Manuel Falcón-Pérez, Javier Olascoaga, David Otaegui
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:International Journal of Molecular Sciences
Subjects:
extracellular vesicles
multiple sclerosis
fingolimod
miRNA
immune regulation
exosomes
Online Access:http://www.mdpi.com/1422-0067/19/8/2448

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