The Cancer Microenvironment: Mechanical Challenges of the Metastatic Cascade
The metastatic cascade presents a significant challenge to patient survival in the fight against cancer. As metastatic cells disseminate and colonize a secondary site, stepwise exposure to microenvironment-specific mechanical stimuli influences and protects successful metastasis. Following cancerous...
Main Authors: | Sebastian E. Amos, Yu Suk Choi |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-02-01
|
Series: | Frontiers in Bioengineering and Biotechnology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2021.625859/full |
Similar Items
-
Mechanics of Cancer Cells in 3D Microenvironments
Published: (2014) -
Matrix stiffness modulates tip cell formation through the p-PXN-Rac1-YAP signaling axis
by: Yaru Guo, et al.
Published: (2022-01-01) -
The Mechanical Microenvironment in Breast Cancer
by: Stephen J.P. Pratt, et al.
Published: (2020-06-01) -
Cellular Pushing Forces during Mitosis Drive Mitotic Elongation in Collagen Gels
by: Sungmin Nam, et al.
Published: (2021-02-01) -
3D Cell Culture for the Study of Microenvironment-Mediated Mechanostimuli to the Cell Nucleus: An Important Step for Cancer Research
by: Apekshya Chhetri, et al.
Published: (2021-02-01)