Cardiac Pathophysiology and the Future of Cardiac Therapies in Duchenne Muscular Dystrophy

Cardiac Pathophysiology and the Future of Cardiac Therapies in Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is a devastating disease featuring skeletal muscle wasting, respiratory insufficiency, and cardiomyopathy. Historically, respiratory failure has been the leading cause of mortality in DMD, but recent improvements in symptomatic respiratory management have extended t...

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Bibliographic Details
Main Authors: Tatyana A. Meyers, DeWayne Townsend
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
Duchenne muscular dystrophy
dystrophic cardiomyopathy
fibrosis
gene therapy
exon skipping
heart disease
Online Access:https://www.mdpi.com/1422-0067/20/17/4098

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