The Ultimate Therapeutic Goal: Establishing and Maintaining Quality of Life

Outcomes in Crohn's disease clinical trials are traditionally reported in terms of remission and response rates according to the Crohn's Disease Activity Index (CDAI), which was developed as part of the National Cooperative Crohn's Disease Study (1). However, it has been argued th...

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Main Author: Remo Panaccione
Format: Article
Language:English
Published: Hindawi Limited 2004-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2004/569262
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spelling doaj-733c971387b14f9c85d0982f9c6876292020-11-24T23:28:25ZengHindawi LimitedCanadian Journal of Gastroenterology0835-79002004-01-0118746546610.1155/2004/569262The Ultimate Therapeutic Goal: Establishing and Maintaining Quality of LifeRemo PanaccioneOutcomes in Crohn's disease clinical trials are traditionally reported in terms of remission and response rates according to the Crohn's Disease Activity Index (CDAI), which was developed as part of the National Cooperative Crohn's Disease Study (1). However, it has been argued that the CDAI does not measure the overall burden of the illness experienced by patients. An alternative is to assess the impact of a particular therapy on health-related quality of life (HRQL). HRQL not only measures the benefits of the therapy on disease symptoms but also is probably better at evaluating the trade-off between therapeutic efficacy and potential adverse effects.http://dx.doi.org/10.1155/2004/569262
collection DOAJ
language English
format Article
sources DOAJ
author Remo Panaccione
spellingShingle Remo Panaccione
The Ultimate Therapeutic Goal: Establishing and Maintaining Quality of Life
Canadian Journal of Gastroenterology
author_facet Remo Panaccione
author_sort Remo Panaccione
title The Ultimate Therapeutic Goal: Establishing and Maintaining Quality of Life
title_short The Ultimate Therapeutic Goal: Establishing and Maintaining Quality of Life
title_full The Ultimate Therapeutic Goal: Establishing and Maintaining Quality of Life
title_fullStr The Ultimate Therapeutic Goal: Establishing and Maintaining Quality of Life
title_full_unstemmed The Ultimate Therapeutic Goal: Establishing and Maintaining Quality of Life
title_sort ultimate therapeutic goal: establishing and maintaining quality of life
publisher Hindawi Limited
series Canadian Journal of Gastroenterology
issn 0835-7900
publishDate 2004-01-01
description Outcomes in Crohn's disease clinical trials are traditionally reported in terms of remission and response rates according to the Crohn's Disease Activity Index (CDAI), which was developed as part of the National Cooperative Crohn's Disease Study (1). However, it has been argued that the CDAI does not measure the overall burden of the illness experienced by patients. An alternative is to assess the impact of a particular therapy on health-related quality of life (HRQL). HRQL not only measures the benefits of the therapy on disease symptoms but also is probably better at evaluating the trade-off between therapeutic efficacy and potential adverse effects.
url http://dx.doi.org/10.1155/2004/569262
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