Enhancing Electrotransfection Efficiency through Improvement in Nuclear Entry of Plasmid DNA

The nuclear envelope is a physiological barrier to electrogene transfer. To understand different mechanisms of the nuclear entry for electrotransfected plasmid DNA (pDNA), the current study investigated how manipulation of the mechanisms could affect electrotransfection efficiency (eTE), transgene e...

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Bibliographic Details
Main Authors: Lisa D. Cervia, Chun-Chi Chang, Liangli Wang, Mao Mao, Fan Yuan
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253118300258