Design, Synthesis, and Biological Evaluation of 4-aminoquinazoline Appended-Benzofuran Hybrids as Epidermal Growth Factor Receptor Inhibitors

Design, Synthesis, and Biological Evaluation of 4-aminoquinazoline Appended-Benzofuran Hybrids as Epidermal Growth Factor Receptor Inhibitors

Nitrogen-containing heterocycles such as quinazolines and benzofurans have received a great amount of interest in targeted therapies as antitumor drugs [1]. [...]

Bibliographic Details
Main Authors: Marole Maria Maluleka, Malose Jack Mphahlele
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Proceedings
Subjects:
n/a
Online Access:https://www.mdpi.com/2504-3900/22/1/22
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spelling doaj-733f3ae38ab34baaaebd034cfa6b30212020-11-25T01:57:01ZengMDPI AGProceedings2504-39002019-08-012212210.3390/proceedings2019022022proceedings2019022022Design, Synthesis, and Biological Evaluation of 4-aminoquinazoline Appended-Benzofuran Hybrids as Epidermal Growth Factor Receptor InhibitorsMarole Maria Maluleka0Malose Jack Mphahlele1Department of Chemistry, College of Science, Engineering and Technology, University of South Africa, Private Bag X06, Florida 1710, South AfricaDepartment of Chemistry, College of Science, Engineering and Technology, University of South Africa, Private Bag X06, Florida 1710, South AfricaNitrogen-containing heterocycles such as quinazolines and benzofurans have received a great amount of interest in targeted therapies as antitumor drugs [1]. [...]https://www.mdpi.com/2504-3900/22/1/22n/a
collection DOAJ
language English
format Article
sources DOAJ
author Marole Maria Maluleka
Malose Jack Mphahlele
spellingShingle Marole Maria Maluleka
Malose Jack Mphahlele
Design, Synthesis, and Biological Evaluation of 4-aminoquinazoline Appended-Benzofuran Hybrids as Epidermal Growth Factor Receptor Inhibitors
Proceedings
n/a
author_facet Marole Maria Maluleka
Malose Jack Mphahlele
author_sort Marole Maria Maluleka
title Design, Synthesis, and Biological Evaluation of 4-aminoquinazoline Appended-Benzofuran Hybrids as Epidermal Growth Factor Receptor Inhibitors
title_short Design, Synthesis, and Biological Evaluation of 4-aminoquinazoline Appended-Benzofuran Hybrids as Epidermal Growth Factor Receptor Inhibitors
title_full Design, Synthesis, and Biological Evaluation of 4-aminoquinazoline Appended-Benzofuran Hybrids as Epidermal Growth Factor Receptor Inhibitors
title_fullStr Design, Synthesis, and Biological Evaluation of 4-aminoquinazoline Appended-Benzofuran Hybrids as Epidermal Growth Factor Receptor Inhibitors
title_full_unstemmed Design, Synthesis, and Biological Evaluation of 4-aminoquinazoline Appended-Benzofuran Hybrids as Epidermal Growth Factor Receptor Inhibitors
title_sort design, synthesis, and biological evaluation of 4-aminoquinazoline appended-benzofuran hybrids as epidermal growth factor receptor inhibitors
publisher MDPI AG
series Proceedings
issn 2504-3900
publishDate 2019-08-01
description Nitrogen-containing heterocycles such as quinazolines and benzofurans have received a great amount of interest in targeted therapies as antitumor drugs [1]. [...]
topic n/a
url https://www.mdpi.com/2504-3900/22/1/22
work_keys_str_mv AT marolemariamaluleka designsynthesisandbiologicalevaluationof4aminoquinazolineappendedbenzofuranhybridsasepidermalgrowthfactorreceptorinhibitors
AT malosejackmphahlele designsynthesisandbiologicalevaluationof4aminoquinazolineappendedbenzofuranhybridsasepidermalgrowthfactorreceptorinhibitors
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