Abundance and diversity of resistomes differ between healthy human oral cavities and gut

Antimicrobial resistance (AMR) represents a global health threat. Here, the authors analyse the oral and gut resistomes from metagenomes of diverse populations and find that the oral resistome harbours higher abundance but lower diversity of antimicrobial resistance genes than the gut resistome.

Bibliographic Details
Main Authors:	Victoria R. Carr, Elizabeth A. Witherden, Sunjae Lee, Saeed Shoaie, Peter Mullany, Gordon B. Proctor, David Gomez-Cabrero, David L. Moyes
Format:	Article
Language:	English
Published:	Nature Publishing Group 2020-02-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-020-14422-w

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spelling	doaj-735991a569e94940aaa4225c473a42a02021-05-11T08:21:44ZengNature Publishing GroupNature Communications2041-17232020-02-0111111010.1038/s41467-020-14422-wAbundance and diversity of resistomes differ between healthy human oral cavities and gutVictoria R. Carr0Elizabeth A. Witherden1Sunjae Lee2Saeed Shoaie3Peter Mullany4Gordon B. Proctor5David Gomez-Cabrero6David L. Moyes7Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King’s College LondonCentre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King’s College LondonCentre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King’s College LondonCentre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King’s College LondonMicrobial Diseases, Eastman Dental Institute, University College LondonCentre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King’s College LondonCentre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King’s College LondonCentre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King’s College LondonAntimicrobial resistance (AMR) represents a global health threat. Here, the authors analyse the oral and gut resistomes from metagenomes of diverse populations and find that the oral resistome harbours higher abundance but lower diversity of antimicrobial resistance genes than the gut resistome.https://doi.org/10.1038/s41467-020-14422-w
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Victoria R. Carr Elizabeth A. Witherden Sunjae Lee Saeed Shoaie Peter Mullany Gordon B. Proctor David Gomez-Cabrero David L. Moyes
spellingShingle	Victoria R. Carr Elizabeth A. Witherden Sunjae Lee Saeed Shoaie Peter Mullany Gordon B. Proctor David Gomez-Cabrero David L. Moyes Abundance and diversity of resistomes differ between healthy human oral cavities and gut Nature Communications
author_facet	Victoria R. Carr Elizabeth A. Witherden Sunjae Lee Saeed Shoaie Peter Mullany Gordon B. Proctor David Gomez-Cabrero David L. Moyes
author_sort	Victoria R. Carr
title	Abundance and diversity of resistomes differ between healthy human oral cavities and gut
title_short	Abundance and diversity of resistomes differ between healthy human oral cavities and gut
title_full	Abundance and diversity of resistomes differ between healthy human oral cavities and gut
title_fullStr	Abundance and diversity of resistomes differ between healthy human oral cavities and gut
title_full_unstemmed	Abundance and diversity of resistomes differ between healthy human oral cavities and gut
title_sort	abundance and diversity of resistomes differ between healthy human oral cavities and gut
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2020-02-01
description	Antimicrobial resistance (AMR) represents a global health threat. Here, the authors analyse the oral and gut resistomes from metagenomes of diverse populations and find that the oral resistome harbours higher abundance but lower diversity of antimicrobial resistance genes than the gut resistome.
url	https://doi.org/10.1038/s41467-020-14422-w
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Abundance and diversity of resistomes differ between healthy human oral cavities and gut

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