In vitro effects of tropisetron and granisetron against Echinococcus granulosus (s.s.) protoscoleces by involvement of calcineurin and calmodulin

In vitro effects of tropisetron and granisetron against Echinococcus granulosus (s.s.) protoscoleces by involvement of calcineurin and calmodulin

Abstract Background Cystic echinococcosis (CE) is a disease caused by the larval stage of Echinococcus granulosus sensu lato  (s.l.). The treatment of CE mainly relies on the use of benzimidazoles, which can commonly cause adverse side effects. Therefore, more efficient treatment options are needed....

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Main Authors: Mohammad Reza Shiee, Eshrat Beigom Kia, Farzaneh Zahabiun, Mahmood Naderi, Elahe Motevaseli, Shahram Nekoeian, Majid Fasihi Harandi, Ahmad Reza Dehpour
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Parasites & Vectors
Subjects:
Tropisetron
Granisetron
Cyclosporine A
Albendazole sulfoxide
Echinococcus granulosus
Calcineurin
Online Access:https://doi.org/10.1186/s13071-021-04691-9

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