Surfactant protein-A modulates LPS-induced TLR4 localization and signaling via β-arrestin 2.

Surfactant protein-A modulates LPS-induced TLR4 localization and signaling via β-arrestin 2.

The soluble C-type lectin surfactant protein (SP)-A mediates lung immune responses partially via its direct effects on alveolar macrophages (AM), the main resident leukocytes exposed to antigens. SP-A modulates the AM threshold of lipopolysaccharide (LPS) activity towards an anti-inflammatory phenot...

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Bibliographic Details
Main Authors:	Vicky Sender, Linda Lang, Cordula Stamme
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3607558?pdf=render

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