Synthesis of 4,4′-(4-Formyl-1<i>H</i>-pyrazole-1,3-diyl)dibenzoic Acid Derivatives as Narrow Spectrum Antibiotics for the Potential Treatment of <i>Acinetobacter Baumannii</i> Infections

Synthesis of 4,4′-(4-Formyl-1<i>H</i>-pyrazole-1,3-diyl)dibenzoic Acid Derivatives as Narrow Spectrum Antibiotics for the Potential Treatment of <i>Acinetobacter Baumannii</i> Infections

<i>Acinetobacter baumannii</i> has emerged as one of the most lethal drug-resistant bacteria in recent years. We report the synthesis and antimicrobial studies of 25 new pyrazole-derived hydrazones. Some of these molecules are potent and specific inhibitors of <i>A. baumannii</i...

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Bibliographic Details
Main Authors:	Evan Delancey, Devin Allison, Hansa Raj KC, David F. Gilmore, Todd Fite, Alexei G. Basnakian, Mohammad A. Alam
Format:	Article
Language:	English
Published:	MDPI AG 2020-09-01
Series:	Antibiotics
Subjects:	antimicrobial pyrazole hydrazone <i>Acinetobacter baumannii</i> toxicity narrow-spectrum antibiotics
Online Access:	https://www.mdpi.com/2079-6382/9/10/650

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