Pathophysiology of the endothelin system - lessons from genetically manipulated animal models

<p>Abstract</p> <p>Shortly after discovery of ET-1 in 1988, the entire endothelin system was characterized. The endothelin system consists of the three peptides ET-1, ET-2 and ET-3, their G-protein-coupled receptors endothelin receptor A and B (ETRA and ETRB) and the two endothelin...

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Bibliographic Details
Main Authors: von Websky K, Heiden S, Pfab T, Hocher B
Format: Article
Language:English
Published: BMC 2009-01-01
Series:European Journal of Medical Research
Online Access:http://www.eurjmedres.com/content/14/1/1