Pregnancy-specific protein B in Yankasa ewes during pregnancy and postpartum periods

• Main Authors: Adewale Ayodeji Adeyeye, Yusha`u Usman Abubakar, Olufisayo Oluwadamilare Leigh, Iyorhembe Utim Ate, Jashilagari Stephen, Kabir Ayo Raheem, Simon Azubuike Ubah
• Format: Article
• Language: English
• Published: Ss.Cyril and Methodius University, Skopje 2021-03-01
• Series: Macedonian Veterinary Review
• Subjects: pregnancy specific protein-b; pregnancy; postpartum; yankasa ewes
• Online Access: https://macvetrev.mk/LoadArticleContent?DOI=10.2478_macvetrev_2021_0010

Pregnancy-specific protein B (PSPB) is produced by mono and binucleate trophoblast cells in the placenta of ruminants during pregnancy. This study was designed to determine the pattern of serum PSPB in Yankasa ewes during pregnancy and postpartum periods. Mature cycling Yankasa ewes were synchronized and divided into two groups A (n=11) and B (n=13). Group A was bred, while group B was unbred. Blood samples for PSPB assessment were collected from the ewes starting from the day of breeding until 4 weeks post-lambing. All pregnant Yankasa ewes lambed with singleton lambs after an average of 151.18 days. There was a significant (p<0.05) increase in PSPB in pregnant compared with the non-pregnant ewes in the period between 3 weeks post-breeding and 3 weeks post-lambing. Peaks were detected in the first (100.60 ng/ml), second (133.90 ng/ml), and third (114.82 ng/ml) trimesters at 5, 10 and 21 weeks of gestation, respectively, but steadily decreased within 4 weeks (2.38 ng/ml) postpartum. In conclusion, PSPB detected pregnancy in Yankasa ewes from 3 weeks post-breeding with peak levels at 5, 10 and 21 weeks post-breeding in the first, second, and third trimesters, respectively. PSPB decreased gradually after lambing until 4 weeks postpartum.