SASP-Dependent Interactions between Senescent Cells and Platelets Modulate Migration and Invasion of Cancer Cells

Alterations in platelet aggregation are common in aging individuals and in the context of age-related pathologies such as cancer. So far, however, the effects of senescent cells on platelets have not been explored. In addition to serving as a barrier to tumor progression, cellular senescence can con...

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Bibliographic Details
Main Authors: Claudio A. Valenzuela, Ricardo Quintanilla, Alexandra Olate-Briones, Whitney Venturini, Daniel Mancilla, Angel Cayo, Rodrigo Moore-Carrasco, Nelson E. Brown
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/20/21/5292