Salivary levels of total huntingtin are elevated in Huntington’s disease patients

Abstract Patients with Huntington’s disease (HD), an autosomal-dominant neurodegenerative disease, show substantial variability in age-of-onset, symptom severity and course of illness, warranting the need for biomarkers to anticipate and monitor these features. The HD gene encodes the disease protei...

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Bibliographic Details
Main Authors: Jody Corey-Bloom, Ameera S. Haque, Sungmee Park, Ajay S. Nathan, Robert W. Baker, Elizabeth A. Thomas
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25095-3