Concurrent endometrial intraepithelial carcinoma (EIC) and endometrial hyperplasia
Endometrial cancer is one of the most common gynecological neoplasms in the United States. It is divided into type I and type II carcinomas based on histological features. The mixed endometrioid (type I) and serous (type II) adenocarcinomas of endometrium were reported in previous studies. The concu...
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doaj-7398ef1c6f1a4905b035a917075cbeb62020-11-25T00:36:00ZengElsevierHuman Pathology: Case Reports2214-33002015-03-01211410.1016/j.ehpc.2014.07.003Concurrent endometrial intraepithelial carcinoma (EIC) and endometrial hyperplasiaSteven Wang, MDZhenglong Wang, MDKhushbakhat Mittal, MDEndometrial cancer is one of the most common gynecological neoplasms in the United States. It is divided into type I and type II carcinomas based on histological features. The mixed endometrioid (type I) and serous (type II) adenocarcinomas of endometrium were reported in previous studies. The concurrence of their precursor lesions was not studied. In current study, we present five cases with concurrent precursor lesions of endometrioid (endometrial hyperplasia) and serous adenocarcinomas (endometrial intraepithelial carcinoma and p53 signature). Due to the potential progressive clinical outcome of precursor lesions of serous adenocarcinoma, caution needs to be performed to identify endometrial intraepithelial carcinoma and p53 signature in the background of endometrial hyperplasia.http://www.sciencedirect.com/science/article/pii/S2214330014200277Endometrial intraepithelial carcinomaEndometrial hyperplasiap53 signatureEndometrial polyp |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Steven Wang, MD Zhenglong Wang, MD Khushbakhat Mittal, MD |
spellingShingle |
Steven Wang, MD Zhenglong Wang, MD Khushbakhat Mittal, MD Concurrent endometrial intraepithelial carcinoma (EIC) and endometrial hyperplasia Human Pathology: Case Reports Endometrial intraepithelial carcinoma Endometrial hyperplasia p53 signature Endometrial polyp |
author_facet |
Steven Wang, MD Zhenglong Wang, MD Khushbakhat Mittal, MD |
author_sort |
Steven Wang, MD |
title |
Concurrent endometrial intraepithelial carcinoma (EIC) and endometrial hyperplasia |
title_short |
Concurrent endometrial intraepithelial carcinoma (EIC) and endometrial hyperplasia |
title_full |
Concurrent endometrial intraepithelial carcinoma (EIC) and endometrial hyperplasia |
title_fullStr |
Concurrent endometrial intraepithelial carcinoma (EIC) and endometrial hyperplasia |
title_full_unstemmed |
Concurrent endometrial intraepithelial carcinoma (EIC) and endometrial hyperplasia |
title_sort |
concurrent endometrial intraepithelial carcinoma (eic) and endometrial hyperplasia |
publisher |
Elsevier |
series |
Human Pathology: Case Reports |
issn |
2214-3300 |
publishDate |
2015-03-01 |
description |
Endometrial cancer is one of the most common gynecological neoplasms in the United States. It is divided into type I and type II carcinomas based on histological features. The mixed endometrioid (type I) and serous (type II) adenocarcinomas of endometrium were reported in previous studies. The concurrence of their precursor lesions was not studied. In current study, we present five cases with concurrent precursor lesions of endometrioid (endometrial hyperplasia) and serous adenocarcinomas (endometrial intraepithelial carcinoma and p53 signature). Due to the potential progressive clinical outcome of precursor lesions of serous adenocarcinoma, caution needs to be performed to identify endometrial intraepithelial carcinoma and p53 signature in the background of endometrial hyperplasia. |
topic |
Endometrial intraepithelial carcinoma Endometrial hyperplasia p53 signature Endometrial polyp |
url |
http://www.sciencedirect.com/science/article/pii/S2214330014200277 |
work_keys_str_mv |
AT stevenwangmd concurrentendometrialintraepithelialcarcinomaeicandendometrialhyperplasia AT zhenglongwangmd concurrentendometrialintraepithelialcarcinomaeicandendometrialhyperplasia AT khushbakhatmittalmd concurrentendometrialintraepithelialcarcinomaeicandendometrialhyperplasia |
_version_ |
1725306512515006464 |