Glycine Oligomerization by Pulsed Discharge Plasma over Aqueous Solution under Atmospheric Pressure
Chemical reactions of amino acids induced by discharge plasma are important for understanding the mechanism of biological effects of discharge plasma in biomedical applications. In this study, we generated a nano-second pulsed discharge plasma under atmospheric pressure over an aqueous solution cont...
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doaj-73ae3dc7a0ad4ef2846ee187ac2ffdf52020-11-25T02:30:51ZengMDPI AGChemEngineering2305-70842018-04-01221710.3390/chemengineering2020017chemengineering2020017Glycine Oligomerization by Pulsed Discharge Plasma over Aqueous Solution under Atmospheric PressureYui Hayashi0Wahyu Diono1Noriharu Takada2Hideki Kanda3Motonobu Goto4Department of Chemical Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, JapanDepartment of Materials Process Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, JapanDepartment of Materials Process Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, JapanDepartment of Materials Process Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, JapanDepartment of Materials Process Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, JapanChemical reactions of amino acids induced by discharge plasma are important for understanding the mechanism of biological effects of discharge plasma in biomedical applications. In this study, we generated a nano-second pulsed discharge plasma under atmospheric pressure over an aqueous solution containing glycine. The reaction products after the pulsed discharge plasma treatments were analyzed by high-performance liquid chromatography and matrix-assisted laser desorption/ionization time-of-flight mass spectroscopy. The oligomerization reaction of glycine was induced in aqueous solution and produced glycine oligomers at the beginning of the discharge plasma. However, the glycine oligomers were decomposed into products with low molecular weight by excessive pulsed discharge plasma. According to comparative experiments, physical force of the plasma is believed to induce the glycine reaction. Moreover, the reactions depended on the pH, but not the conductivity, of the glycine solution. Glycine in aqueous solution was reacted by the discharge plasma only at neutral pH because the reaction proceeded only when glycine ions were in the zwitterionic state. Anions and cations of glycine reacted very little under the discharge plasma.http://www.mdpi.com/2305-7084/2/2/17amino acidspulsed discharge plasmaoligomerizationglycineprotein |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Yui Hayashi Wahyu Diono Noriharu Takada Hideki Kanda Motonobu Goto |
spellingShingle |
Yui Hayashi Wahyu Diono Noriharu Takada Hideki Kanda Motonobu Goto Glycine Oligomerization by Pulsed Discharge Plasma over Aqueous Solution under Atmospheric Pressure ChemEngineering amino acids pulsed discharge plasma oligomerization glycine protein |
author_facet |
Yui Hayashi Wahyu Diono Noriharu Takada Hideki Kanda Motonobu Goto |
author_sort |
Yui Hayashi |
title |
Glycine Oligomerization by Pulsed Discharge Plasma over Aqueous Solution under Atmospheric Pressure |
title_short |
Glycine Oligomerization by Pulsed Discharge Plasma over Aqueous Solution under Atmospheric Pressure |
title_full |
Glycine Oligomerization by Pulsed Discharge Plasma over Aqueous Solution under Atmospheric Pressure |
title_fullStr |
Glycine Oligomerization by Pulsed Discharge Plasma over Aqueous Solution under Atmospheric Pressure |
title_full_unstemmed |
Glycine Oligomerization by Pulsed Discharge Plasma over Aqueous Solution under Atmospheric Pressure |
title_sort |
glycine oligomerization by pulsed discharge plasma over aqueous solution under atmospheric pressure |
publisher |
MDPI AG |
series |
ChemEngineering |
issn |
2305-7084 |
publishDate |
2018-04-01 |
description |
Chemical reactions of amino acids induced by discharge plasma are important for understanding the mechanism of biological effects of discharge plasma in biomedical applications. In this study, we generated a nano-second pulsed discharge plasma under atmospheric pressure over an aqueous solution containing glycine. The reaction products after the pulsed discharge plasma treatments were analyzed by high-performance liquid chromatography and matrix-assisted laser desorption/ionization time-of-flight mass spectroscopy. The oligomerization reaction of glycine was induced in aqueous solution and produced glycine oligomers at the beginning of the discharge plasma. However, the glycine oligomers were decomposed into products with low molecular weight by excessive pulsed discharge plasma. According to comparative experiments, physical force of the plasma is believed to induce the glycine reaction. Moreover, the reactions depended on the pH, but not the conductivity, of the glycine solution. Glycine in aqueous solution was reacted by the discharge plasma only at neutral pH because the reaction proceeded only when glycine ions were in the zwitterionic state. Anions and cations of glycine reacted very little under the discharge plasma. |
topic |
amino acids pulsed discharge plasma oligomerization glycine protein |
url |
http://www.mdpi.com/2305-7084/2/2/17 |
work_keys_str_mv |
AT yuihayashi glycineoligomerizationbypulseddischargeplasmaoveraqueoussolutionunderatmosphericpressure AT wahyudiono glycineoligomerizationbypulseddischargeplasmaoveraqueoussolutionunderatmosphericpressure AT noriharutakada glycineoligomerizationbypulseddischargeplasmaoveraqueoussolutionunderatmosphericpressure AT hidekikanda glycineoligomerizationbypulseddischargeplasmaoveraqueoussolutionunderatmosphericpressure AT motonobugoto glycineoligomerizationbypulseddischargeplasmaoveraqueoussolutionunderatmosphericpressure |
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1724827330118942720 |