Triterpenoids from Azorella trifurcata (Gaertn.) Pers and their effect against the enzyme acetylcholinesterase

Triterpenoids from Azorella trifurcata (Gaertn.) Pers and their effect against the enzyme acetylcholinesterase

The inhibition of the enzyme acetylcholinesterase is considered as a strategy for the treatment of Alzheimer's disease, senile dementia, ataxia, and myasthenia gravis. Three lanostane- and two cycloartane-type triterpenes, together with two mulinane-type diterpenes were isolated from petroleum...

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Main Authors: Carlos Areche, Patricia Cejas, Pablo Thomas, Aurelio San-Martín, Luis Astudillo, Margarita Gutiérrez, Luis A Loyola
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2009-01-01
Series:Química Nova
Subjects:
Azorella
Umbelliferae
triterpenes
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000800008
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spelling doaj-73db57c9207546e799a8c4bfc25641da2020-11-25T00:31:01ZengSociedade Brasileira de QuímicaQuímica Nova0100-40421678-70642009-01-013282023202510.1590/S0100-40422009000800008Triterpenoids from Azorella trifurcata (Gaertn.) Pers and their effect against the enzyme acetylcholinesteraseCarlos ArechePatricia CejasPablo ThomasAurelio San-MartínLuis AstudilloMargarita GutiérrezLuis A LoyolaThe inhibition of the enzyme acetylcholinesterase is considered as a strategy for the treatment of Alzheimer's disease, senile dementia, ataxia, and myasthenia gravis. Three lanostane- and two cycloartane-type triterpenes, together with two mulinane-type diterpenes were isolated from petroleum ether extract of the whole shrub of Azorella trifurcata (Gaertn.) Pers. Their effect on the enzyme acetylcholinesterase was assessed as well. In addition, this is the first report of these triterpenes in the genus Azorella.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000800008AzorellaUmbelliferaetriterpenes
collection DOAJ
language English
format Article
sources DOAJ
author Carlos Areche
Patricia Cejas
Pablo Thomas
Aurelio San-Martín
Luis Astudillo
Margarita Gutiérrez
Luis A Loyola
spellingShingle Carlos Areche
Patricia Cejas
Pablo Thomas
Aurelio San-Martín
Luis Astudillo
Margarita Gutiérrez
Luis A Loyola
Triterpenoids from Azorella trifurcata (Gaertn.) Pers and their effect against the enzyme acetylcholinesterase
Química Nova
Azorella
Umbelliferae
triterpenes
author_facet Carlos Areche
Patricia Cejas
Pablo Thomas
Aurelio San-Martín
Luis Astudillo
Margarita Gutiérrez
Luis A Loyola
author_sort Carlos Areche
title Triterpenoids from Azorella trifurcata (Gaertn.) Pers and their effect against the enzyme acetylcholinesterase
title_short Triterpenoids from Azorella trifurcata (Gaertn.) Pers and their effect against the enzyme acetylcholinesterase
title_full Triterpenoids from Azorella trifurcata (Gaertn.) Pers and their effect against the enzyme acetylcholinesterase
title_fullStr Triterpenoids from Azorella trifurcata (Gaertn.) Pers and their effect against the enzyme acetylcholinesterase
title_full_unstemmed Triterpenoids from Azorella trifurcata (Gaertn.) Pers and their effect against the enzyme acetylcholinesterase
title_sort triterpenoids from azorella trifurcata (gaertn.) pers and their effect against the enzyme acetylcholinesterase
publisher Sociedade Brasileira de Química
series Química Nova
issn 0100-4042
1678-7064
publishDate 2009-01-01
description The inhibition of the enzyme acetylcholinesterase is considered as a strategy for the treatment of Alzheimer's disease, senile dementia, ataxia, and myasthenia gravis. Three lanostane- and two cycloartane-type triterpenes, together with two mulinane-type diterpenes were isolated from petroleum ether extract of the whole shrub of Azorella trifurcata (Gaertn.) Pers. Their effect on the enzyme acetylcholinesterase was assessed as well. In addition, this is the first report of these triterpenes in the genus Azorella.
topic Azorella
Umbelliferae
triterpenes
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000800008
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