Repeated Restraint Stress Led to Cognitive Dysfunction by NMDA Receptor-Mediated Hippocampal CA3 Dendritic Spine Impairments in Juvenile Sprague-Dawley Rats

Repeated Restraint Stress Led to Cognitive Dysfunction by NMDA Receptor-Mediated Hippocampal CA3 Dendritic Spine Impairments in Juvenile Sprague-Dawley Rats

Although numerous studies have indicated that chronic stress causes cognitive dysfunction with the impairment of synaptic structures and functions, the relationship between cognitive deficits induced by repeated restraint stress and the level of NMDA receptors in the subregion of the hippocampus has...

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Bibliographic Details
Main Authors: Dong-sheng Sun, Gang Zhong, Hong-Xia Cao, Yu Hu, Xiao-Yue Hong, Ting Li, Xiao Li, Qian Liu, Qun Wang, Dan Ke, Gong-ping Liu, Rong-Hong Ma, Dan-Ju Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
chronic stress
cognitive dysfunction
NMDA receptors
CA3 region
hippocampus
synaptic impairment
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2020.552787/full

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