<i>Akkermansia</i> and Microbial Degradation of Mucus in Cats and Dogs: Implications to the Growing Worldwide Epidemic of Pet Obesity
<i>Akkermansia muciniphila</i> is a mucin-degrading bacterium that has shown the potential to provide anti-inflammatory and anti-obesity effects in mouse and man. We here focus on companion animals, specifically cats and dogs, and evaluate the microbial degradation of mucus and its healt...
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doaj-73e470386e454026aed9b81a733094f52021-04-02T14:56:11ZengMDPI AGVeterinary Sciences2306-73812020-04-017444410.3390/vetsci7020044<i>Akkermansia</i> and Microbial Degradation of Mucus in Cats and Dogs: Implications to the Growing Worldwide Epidemic of Pet ObesityJose F. Garcia-Mazcorro0Yasushi Minamoto1Jorge R. Kawas2Jan S. Suchodolski3Willem M. de Vos4Research and Development, MNA de Mexico, San Nicolas de los Garza, Nuevo Leon 66477, MexicoAnimal Emergency & Specialty, Kirkland, WA 98034, USAFaculty of Agronomy, Universidad Autonoma de Nuevo Leon, General Escobedo, Nuevo Leon 66050, MexicoGastrointestinal Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843-4474, USALaboratory of Microbiology, Wageningen University, 6708 WE Wageningen, The Netherlands<i>Akkermansia muciniphila</i> is a mucin-degrading bacterium that has shown the potential to provide anti-inflammatory and anti-obesity effects in mouse and man. We here focus on companion animals, specifically cats and dogs, and evaluate the microbial degradation of mucus and its health impact in the context of the worldwide epidemic of pet obesity. A literature survey revealed that the two presently known <i>Akkermansia</i> spp., <i>A. muciniphila</i> and <i>A. glycaniphila</i>, as well as other members of the phylum of Verrucomicrobia seem to be neither very prevalent nor abundant in the digestive tract of cats and dog. While this may be due to methodological aspects, it suggests that bacteria related to <i>Akkermansia</i> are not the major mucus degraders in these pets and hence other mucus-utilizing taxa may deserve attention. Hence, we will discuss the potential of these endogenous mucus utilizers and dietary interventions to boost these as well as the use of <i>Akkermansia</i> spp. related bacteria or their components as strategies to target feline and canine obesity.https://www.mdpi.com/2306-7381/7/2/44feline obesitycanine obesitymucus degradationcompanion animals |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jose F. Garcia-Mazcorro Yasushi Minamoto Jorge R. Kawas Jan S. Suchodolski Willem M. de Vos |
spellingShingle |
Jose F. Garcia-Mazcorro Yasushi Minamoto Jorge R. Kawas Jan S. Suchodolski Willem M. de Vos <i>Akkermansia</i> and Microbial Degradation of Mucus in Cats and Dogs: Implications to the Growing Worldwide Epidemic of Pet Obesity Veterinary Sciences feline obesity canine obesity mucus degradation companion animals |
author_facet |
Jose F. Garcia-Mazcorro Yasushi Minamoto Jorge R. Kawas Jan S. Suchodolski Willem M. de Vos |
author_sort |
Jose F. Garcia-Mazcorro |
title |
<i>Akkermansia</i> and Microbial Degradation of Mucus in Cats and Dogs: Implications to the Growing Worldwide Epidemic of Pet Obesity |
title_short |
<i>Akkermansia</i> and Microbial Degradation of Mucus in Cats and Dogs: Implications to the Growing Worldwide Epidemic of Pet Obesity |
title_full |
<i>Akkermansia</i> and Microbial Degradation of Mucus in Cats and Dogs: Implications to the Growing Worldwide Epidemic of Pet Obesity |
title_fullStr |
<i>Akkermansia</i> and Microbial Degradation of Mucus in Cats and Dogs: Implications to the Growing Worldwide Epidemic of Pet Obesity |
title_full_unstemmed |
<i>Akkermansia</i> and Microbial Degradation of Mucus in Cats and Dogs: Implications to the Growing Worldwide Epidemic of Pet Obesity |
title_sort |
<i>akkermansia</i> and microbial degradation of mucus in cats and dogs: implications to the growing worldwide epidemic of pet obesity |
publisher |
MDPI AG |
series |
Veterinary Sciences |
issn |
2306-7381 |
publishDate |
2020-04-01 |
description |
<i>Akkermansia muciniphila</i> is a mucin-degrading bacterium that has shown the potential to provide anti-inflammatory and anti-obesity effects in mouse and man. We here focus on companion animals, specifically cats and dogs, and evaluate the microbial degradation of mucus and its health impact in the context of the worldwide epidemic of pet obesity. A literature survey revealed that the two presently known <i>Akkermansia</i> spp., <i>A. muciniphila</i> and <i>A. glycaniphila</i>, as well as other members of the phylum of Verrucomicrobia seem to be neither very prevalent nor abundant in the digestive tract of cats and dog. While this may be due to methodological aspects, it suggests that bacteria related to <i>Akkermansia</i> are not the major mucus degraders in these pets and hence other mucus-utilizing taxa may deserve attention. Hence, we will discuss the potential of these endogenous mucus utilizers and dietary interventions to boost these as well as the use of <i>Akkermansia</i> spp. related bacteria or their components as strategies to target feline and canine obesity. |
topic |
feline obesity canine obesity mucus degradation companion animals |
url |
https://www.mdpi.com/2306-7381/7/2/44 |
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