An integrated in vivo/in vitro framework to enhance cell-free biosynthesis with metabolically rewired yeast extracts

Cell-free systems enable the design of biosynthetic pathways for sustainable chemical synthesis. Here the authors create an integrated framework for accelerating design using extracts from genetically rewired strains.

Bibliographic Details
Main Authors:	Blake J. Rasor, Xiunan Yi, Hunter Brown, Hal S. Alper, Michael C. Jewett
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-08-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-021-25233-y

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spelling	doaj-73f60a6b74f34dd9b16350ac7a8f3a1f2021-08-29T11:38:14ZengNature Publishing GroupNature Communications2041-17232021-08-011211910.1038/s41467-021-25233-yAn integrated in vivo/in vitro framework to enhance cell-free biosynthesis with metabolically rewired yeast extractsBlake J. Rasor0Xiunan Yi1Hunter Brown2Hal S. Alper3Michael C. Jewett4Department of Chemical and Biological Engineering, Northwestern UniversityInstitute for Cellular and Molecular Biology, The University of Texas at AustinDepartment of Chemical and Biological Engineering, Northwestern UniversityInstitute for Cellular and Molecular Biology, The University of Texas at AustinDepartment of Chemical and Biological Engineering, Northwestern UniversityCell-free systems enable the design of biosynthetic pathways for sustainable chemical synthesis. Here the authors create an integrated framework for accelerating design using extracts from genetically rewired strains.https://doi.org/10.1038/s41467-021-25233-y
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Blake J. Rasor Xiunan Yi Hunter Brown Hal S. Alper Michael C. Jewett
spellingShingle	Blake J. Rasor Xiunan Yi Hunter Brown Hal S. Alper Michael C. Jewett An integrated in vivo/in vitro framework to enhance cell-free biosynthesis with metabolically rewired yeast extracts Nature Communications
author_facet	Blake J. Rasor Xiunan Yi Hunter Brown Hal S. Alper Michael C. Jewett
author_sort	Blake J. Rasor
title	An integrated in vivo/in vitro framework to enhance cell-free biosynthesis with metabolically rewired yeast extracts
title_short	An integrated in vivo/in vitro framework to enhance cell-free biosynthesis with metabolically rewired yeast extracts
title_full	An integrated in vivo/in vitro framework to enhance cell-free biosynthesis with metabolically rewired yeast extracts
title_fullStr	An integrated in vivo/in vitro framework to enhance cell-free biosynthesis with metabolically rewired yeast extracts
title_full_unstemmed	An integrated in vivo/in vitro framework to enhance cell-free biosynthesis with metabolically rewired yeast extracts
title_sort	integrated in vivo/in vitro framework to enhance cell-free biosynthesis with metabolically rewired yeast extracts
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2021-08-01
description	Cell-free systems enable the design of biosynthetic pathways for sustainable chemical synthesis. Here the authors create an integrated framework for accelerating design using extracts from genetically rewired strains.
url	https://doi.org/10.1038/s41467-021-25233-y
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An integrated in vivo/in vitro framework to enhance cell-free biosynthesis with metabolically rewired yeast extracts

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