Shared mechanisms in stemness and carcinogenesis: lessons from oncogenic viruses

Shared mechanisms in stemness and carcinogenesis: lessons from oncogenic viruses

A rise in technologies for epigenetic reprogramming of cells to pluripotency highlights the potential of understanding and manipulating cellular plasticity in unprecedented ways. Increasing evidence points to shared mechanisms between cellular reprogramming and the carcinogenic process, with the eme...

Full description

Bibliographic Details
Main Authors: Demetris eIacovides, Stella eMichael, Charis eAchilleos, Katerina eStrati
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Cancer
KSHV
ebv
HPV
HBV
HCV
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2013.00066/full
Description
Summary:A rise in technologies for epigenetic reprogramming of cells to pluripotency highlights the potential of understanding and manipulating cellular plasticity in unprecedented ways. Increasing evidence points to shared mechanisms between cellular reprogramming and the carcinogenic process, with the emerging possibility to harness these parallels in future therapeutics. In this review, we present a synopsis of recent work from oncogenic viruses which contributes to this body of knowledge, establishing a nexus between infection, cancer and stemness.
ISSN:2235-2988

Similar Items