Shared mechanisms in stemness and carcinogenesis: lessons from oncogenic viruses

Shared mechanisms in stemness and carcinogenesis: lessons from oncogenic viruses

A rise in technologies for epigenetic reprogramming of cells to pluripotency highlights the potential of understanding and manipulating cellular plasticity in unprecedented ways. Increasing evidence points to shared mechanisms between cellular reprogramming and the carcinogenic process, with the eme...

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Main Authors: Demetris eIacovides, Stella eMichael, Charis eAchilleos, Katerina eStrati
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Cancer
KSHV
ebv
HPV
HBV
HCV
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2013.00066/full
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spelling doaj-73f64401fa9d46b8a1b1421fbd3e11202020-11-24T23:28:49ZengFrontiers Media S.A.Frontiers in Cellular and Infection Microbiology2235-29882013-12-01310.3389/fcimb.2013.0006664650Shared mechanisms in stemness and carcinogenesis: lessons from oncogenic virusesDemetris eIacovides0Stella eMichael1Charis eAchilleos2Katerina eStrati3University of CyprusUniversity of CyprusUniversity of CyprusUniversity of CyprusA rise in technologies for epigenetic reprogramming of cells to pluripotency highlights the potential of understanding and manipulating cellular plasticity in unprecedented ways. Increasing evidence points to shared mechanisms between cellular reprogramming and the carcinogenic process, with the emerging possibility to harness these parallels in future therapeutics. In this review, we present a synopsis of recent work from oncogenic viruses which contributes to this body of knowledge, establishing a nexus between infection, cancer and stemness.http://journal.frontiersin.org/Journal/10.3389/fcimb.2013.00066/fullCancerKSHVebvHPVHBVHCV
collection DOAJ
language English
format Article
sources DOAJ
author Demetris eIacovides
Stella eMichael
Charis eAchilleos
Katerina eStrati
spellingShingle Demetris eIacovides
Stella eMichael
Charis eAchilleos
Katerina eStrati
Shared mechanisms in stemness and carcinogenesis: lessons from oncogenic viruses
Frontiers in Cellular and Infection Microbiology
Cancer
KSHV
ebv
HPV
HBV
HCV
author_facet Demetris eIacovides
Stella eMichael
Charis eAchilleos
Katerina eStrati
author_sort Demetris eIacovides
title Shared mechanisms in stemness and carcinogenesis: lessons from oncogenic viruses
title_short Shared mechanisms in stemness and carcinogenesis: lessons from oncogenic viruses
title_full Shared mechanisms in stemness and carcinogenesis: lessons from oncogenic viruses
title_fullStr Shared mechanisms in stemness and carcinogenesis: lessons from oncogenic viruses
title_full_unstemmed Shared mechanisms in stemness and carcinogenesis: lessons from oncogenic viruses
title_sort shared mechanisms in stemness and carcinogenesis: lessons from oncogenic viruses
publisher Frontiers Media S.A.
series Frontiers in Cellular and Infection Microbiology
issn 2235-2988
publishDate 2013-12-01
description A rise in technologies for epigenetic reprogramming of cells to pluripotency highlights the potential of understanding and manipulating cellular plasticity in unprecedented ways. Increasing evidence points to shared mechanisms between cellular reprogramming and the carcinogenic process, with the emerging possibility to harness these parallels in future therapeutics. In this review, we present a synopsis of recent work from oncogenic viruses which contributes to this body of knowledge, establishing a nexus between infection, cancer and stemness.
topic Cancer
KSHV
ebv
HPV
HBV
HCV
url http://journal.frontiersin.org/Journal/10.3389/fcimb.2013.00066/full
work_keys_str_mv AT demetriseiacovides sharedmechanismsinstemnessandcarcinogenesislessonsfromoncogenicviruses
AT stellaemichael sharedmechanismsinstemnessandcarcinogenesislessonsfromoncogenicviruses
AT chariseachilleos sharedmechanismsinstemnessandcarcinogenesislessonsfromoncogenicviruses
AT katerinaestrati sharedmechanismsinstemnessandcarcinogenesislessonsfromoncogenicviruses
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