B cells contribute to heterogeneity of IL-17 producing cells in rheumatoid arthritis and healthy controls.

B cells contribute to heterogeneity of IL-17 producing cells in rheumatoid arthritis and healthy controls.

Secretion of the proinflammatory cytokine Interleukin-17A (IL-17A) is the hallmark of a unique lineage of CD4 T cells designated Th17 cells, which may play a crucial role in the pathogenesis of rheumatoid arthritis (RA) and many autoimmune diseases. Recently, IL-17-producing cells other than T cells...

Full description

Bibliographic Details
Main Authors: Paul Martin Schlegel, Ingeborg Steiert, Ina Kötter, Claudia A Müller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3855537?pdf=render

Similar Items

Similar Items