Use of Ustekinumab in the Treatment of Libyan Psoriasis Vulgaris Patients

Introduction. Psoriasis is a relatively common chronic inflammatory disease. It clinically manifests as raised, well defined erythematous plaques with irregular borders and silvery scales. Psoriasis appears to be mediated by abnormal immune system functioning, including T lymphocyte and macrophage a...

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Main Authors: Beltammer Belkais, Gargoom Ali, Taeib Ghada, Duweb Gamal
Format: Article
Language:English
Published: Sciendo 2019-03-01
Series:Serbian Journal of Dermatology and Venereology
Subjects:
Online Access:https://doi.org/10.2478/sjdv-2019-0002
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spelling doaj-74069b33f7c9439cbdd896c958e4f9482021-09-05T14:01:55ZengSciendoSerbian Journal of Dermatology and Venereology1821-09022406-06312019-03-01111131810.2478/sjdv-2019-0002sjdv-2019-0002Use of Ustekinumab in the Treatment of Libyan Psoriasis Vulgaris PatientsBeltammer Belkais0Gargoom Ali1Taeib Ghada2Duweb Gamal3Dermatology Department, Faculty of Medicine, Benghazi University, Benghazi-LibyaDermatology Department, Faculty of Medicine, Benghazi University, Benghazi-LibyaDermatology Department, Faculty of Medicine, Benghazi University, Benghazi-LibyaDermatology Department, Faculty of Medicine, Benghazi University, Benghazi-LibyaIntroduction. Psoriasis is a relatively common chronic inflammatory disease. It clinically manifests as raised, well defined erythematous plaques with irregular borders and silvery scales. Psoriasis appears to be mediated by abnormal immune system functioning, including T lymphocyte and macrophage activation and release of various cytokins, such as interleukin 12 (IL-12) and IL-23. Recently a new biologic agent Ustekinumab has been used in the treatment of psoriasis. Our aim in this study was to assess the efficacy and tolerability of ustekinumab in moderate to severe psoriasis vulgaris and to observe and report any adverse reaction.https://doi.org/10.2478/sjdv-2019-0002psoriasisustekinumabdermatologic agentsbiological therapytreatment outcomelibya
collection DOAJ
language English
format Article
sources DOAJ
author Beltammer Belkais
Gargoom Ali
Taeib Ghada
Duweb Gamal
spellingShingle Beltammer Belkais
Gargoom Ali
Taeib Ghada
Duweb Gamal
Use of Ustekinumab in the Treatment of Libyan Psoriasis Vulgaris Patients
Serbian Journal of Dermatology and Venereology
psoriasis
ustekinumab
dermatologic agents
biological therapy
treatment outcome
libya
author_facet Beltammer Belkais
Gargoom Ali
Taeib Ghada
Duweb Gamal
author_sort Beltammer Belkais
title Use of Ustekinumab in the Treatment of Libyan Psoriasis Vulgaris Patients
title_short Use of Ustekinumab in the Treatment of Libyan Psoriasis Vulgaris Patients
title_full Use of Ustekinumab in the Treatment of Libyan Psoriasis Vulgaris Patients
title_fullStr Use of Ustekinumab in the Treatment of Libyan Psoriasis Vulgaris Patients
title_full_unstemmed Use of Ustekinumab in the Treatment of Libyan Psoriasis Vulgaris Patients
title_sort use of ustekinumab in the treatment of libyan psoriasis vulgaris patients
publisher Sciendo
series Serbian Journal of Dermatology and Venereology
issn 1821-0902
2406-0631
publishDate 2019-03-01
description Introduction. Psoriasis is a relatively common chronic inflammatory disease. It clinically manifests as raised, well defined erythematous plaques with irregular borders and silvery scales. Psoriasis appears to be mediated by abnormal immune system functioning, including T lymphocyte and macrophage activation and release of various cytokins, such as interleukin 12 (IL-12) and IL-23. Recently a new biologic agent Ustekinumab has been used in the treatment of psoriasis. Our aim in this study was to assess the efficacy and tolerability of ustekinumab in moderate to severe psoriasis vulgaris and to observe and report any adverse reaction.
topic psoriasis
ustekinumab
dermatologic agents
biological therapy
treatment outcome
libya
url https://doi.org/10.2478/sjdv-2019-0002
work_keys_str_mv AT beltammerbelkais useofustekinumabinthetreatmentoflibyanpsoriasisvulgarispatients
AT gargoomali useofustekinumabinthetreatmentoflibyanpsoriasisvulgarispatients
AT taeibghada useofustekinumabinthetreatmentoflibyanpsoriasisvulgarispatients
AT duwebgamal useofustekinumabinthetreatmentoflibyanpsoriasisvulgarispatients
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