MTDH associates with m6A RNA methylation and predicts cancer response for immune checkpoint treatment

MTDH associates with m6A RNA methylation and predicts cancer response for immune checkpoint treatment

Summary: Immune checkpoint blockade (ICB) persistently provides a prognosis improvement but only in a small fraction of patients with cancer due to immunotherapy resistance induced by the consecutive activated oncogenic pathways, including MAPK, Akt, and WNT pathway partially driven by Metadherin (M...

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Bibliographic Details
Main Authors: Fen Zhang, Huimei Huang, Yuexiang Qin, Changhan Chen, Li She, Juncheng Wang, Donghai Huang, Qinglai Tang, Yong Liu, Gangcai Zhu, Xin Zhang
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:iScience
Subjects:
Biological sciences
Molecular biology
Expression study
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221010701

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http://www.sciencedirect.com/science/article/pii/S2589004221010701

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