Cord blood derived CD4+ CD25(high) T cells become functional regulatory T cells upon antigen encounter.

Cord blood derived CD4+ CD25(high) T cells become functional regulatory T cells upon antigen encounter.

BACKGROUND: Upon antigen exposure, cord blood derived T cells respond to ubiquitous environmental antigens by high proliferation. To date it remains unclear whether these "excessive" responses relate to different regulatory properties of the putative T regulatory cell (Treg) compartment or...

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Bibliographic Details
Main Authors:	Elisabeth Mayer, Christina Bannert, Saskia Gruber, Sven Klunker, Andreas Spittler, Cezmi A Akdis, Zsolt Szépfalusi, Thomas Eiwegger
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3260151?pdf=render

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