Plasma Proteome Profiling to detect and avoid sample‐related biases in biomarker studies

Plasma Proteome Profiling to detect and avoid sample‐related biases in biomarker studies

Abstract Plasma and serum are rich sources of information regarding an individual's health state, and protein tests inform medical decision making. Despite major investments, few new biomarkers have reached the clinic. Mass spectrometry (MS)‐based proteomics now allows highly specific and quant...

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Bibliographic Details
Main Authors: Philipp E Geyer, Eugenia Voytik, Peter V Treit, Sophia Doll, Alisa Kleinhempel, Lili Niu, Johannes B Müller, Marie‐Luise Buchholtz, Jakob M Bader, Daniel Teupser, Lesca M Holdt, Matthias Mann
Format: Article
Language:English
Published: Wiley 2019-11-01
Series:EMBO Molecular Medicine
Subjects:
biomarker discovery
mass spectrometry
plasma proteomics
sample quality
study design
Online Access:https://doi.org/10.15252/emmm.201910427

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