Increased frontal electroencephalogram theta amplitude in patients with anorexia nervosa compared to healthy controls
Knut A Hestad,1–3 Siri Weider,3,4 Kristian Bernhard Nilsen,5–7 Marit Sæbø Indredavik,8,9 Trond Sand7,10 1Department of Research, Innlandet Hospital Trust, Brumunddal, Norway; 2Department of Public Health, Hedmark University of Applied Sciences, Elverum, Norw...
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doaj-7417fadd29704eee8ceb216ef44f752a2020-11-24T23:52:46ZengDove Medical PressNeuropsychiatric Disease and Treatment1178-20212016-09-01Volume 122419242329052Increased frontal electroencephalogram theta amplitude in patients with anorexia nervosa compared to healthy controlsHestad KAWeider SNilsen KBIndredavik MSSTKnut A Hestad,1–3 Siri Weider,3,4 Kristian Bernhard Nilsen,5–7 Marit Sæbø Indredavik,8,9 Trond Sand7,10 1Department of Research, Innlandet Hospital Trust, Brumunddal, Norway; 2Department of Public Health, Hedmark University of Applied Sciences, Elverum, Norway; 3Department of Psychology, Faculty of Social Sciences and Technology Management, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; 4Department of Psychiatry, Specialised Unit for Eating Disorder Patients, Levanger Hospital, Health Trust Nord-Trøndelag, Levanger, Norway; 5Department of Neuroscience, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; 6Department of Work Psychology and Physiology, National Institute of Occupational Health, Oslo, Norway; 7Department of Neurology, Section for Clinical Neurophysiology, Oslo University Hospital, Ullevål, Oslo, Norway; 8Regional Centre for Child and Youth Mental Health and Child Welfare, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; 9Department of Child and Adolescent Psychiatry, St Olavs Hospital, Trondheim University Hospital, Trondheim, Norway; 10Department of Neurology and Clinical Neurophysiology, St Olavs Hospital, Trondheim University Hospital, Trondheim, Norway Objective: To conduct a blind study of quantitative electroencephalogram-band amplitudes in patients with anorexia nervosa (AN) and healthy controls.Methods: Twenty-one patients with AN and 24 controls were examined with eyes-closed 16-channel electroencephalogram. Main variables were absolute alpha, theta, and delta amplitudes in frontal, temporal, and posterior regions.Results: There were no significant differences between the AN patients and controls regarding absolute regional band amplitudes in µV. Borderline significance was found for anterior theta (P=0.051). Significantly increased left and right frontal electrode theta amplitude was found in AN patients (F3, P=0.014; F4, P=0.038) compared to controls. Significant differences were also observed for secondary variables: lower values for relative parietooccipital delta and frontocentral alpha activity among AN patients than among controls.Conclusion: We observed slight excess frontal theta and lower relative alpha and delta amplitudes among AN patients than among controls. This pattern is possibly related to a slight frontal lobe dysfunction in AN, or it may reflect increased attention/vigilance or another state-related change in patients with AN compared to healthy controls. Keywords: anorexia, EEG, frontal theta, alpha, delta, eating disordershttps://www.dovepress.com/increased-frontal-electroencephalogram-theta-amplitude-in-patients-wit-peer-reviewed-article-NDTAnorexiaEEGqEEGfrontal thetaalphadelta. |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Hestad KA Weider S Nilsen KB Indredavik MS S T |
spellingShingle |
Hestad KA Weider S Nilsen KB Indredavik MS S T Increased frontal electroencephalogram theta amplitude in patients with anorexia nervosa compared to healthy controls Neuropsychiatric Disease and Treatment Anorexia EEG qEEG frontal theta alpha delta. |
author_facet |
Hestad KA Weider S Nilsen KB Indredavik MS S T |
author_sort |
Hestad KA |
title |
Increased frontal electroencephalogram theta amplitude in patients with anorexia nervosa compared to healthy controls |
title_short |
Increased frontal electroencephalogram theta amplitude in patients with anorexia nervosa compared to healthy controls |
title_full |
Increased frontal electroencephalogram theta amplitude in patients with anorexia nervosa compared to healthy controls |
title_fullStr |
Increased frontal electroencephalogram theta amplitude in patients with anorexia nervosa compared to healthy controls |
title_full_unstemmed |
Increased frontal electroencephalogram theta amplitude in patients with anorexia nervosa compared to healthy controls |
title_sort |
increased frontal electroencephalogram theta amplitude in patients with anorexia nervosa compared to healthy controls |
publisher |
Dove Medical Press |
series |
Neuropsychiatric Disease and Treatment |
issn |
1178-2021 |
publishDate |
2016-09-01 |
description |
Knut A Hestad,1–3 Siri Weider,3,4 Kristian Bernhard Nilsen,5–7 Marit Sæbø Indredavik,8,9 Trond Sand7,10 1Department of Research, Innlandet Hospital Trust, Brumunddal, Norway; 2Department of Public Health, Hedmark University of Applied Sciences, Elverum, Norway; 3Department of Psychology, Faculty of Social Sciences and Technology Management, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; 4Department of Psychiatry, Specialised Unit for Eating Disorder Patients, Levanger Hospital, Health Trust Nord-Trøndelag, Levanger, Norway; 5Department of Neuroscience, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; 6Department of Work Psychology and Physiology, National Institute of Occupational Health, Oslo, Norway; 7Department of Neurology, Section for Clinical Neurophysiology, Oslo University Hospital, Ullevål, Oslo, Norway; 8Regional Centre for Child and Youth Mental Health and Child Welfare, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; 9Department of Child and Adolescent Psychiatry, St Olavs Hospital, Trondheim University Hospital, Trondheim, Norway; 10Department of Neurology and Clinical Neurophysiology, St Olavs Hospital, Trondheim University Hospital, Trondheim, Norway Objective: To conduct a blind study of quantitative electroencephalogram-band amplitudes in patients with anorexia nervosa (AN) and healthy controls.Methods: Twenty-one patients with AN and 24 controls were examined with eyes-closed 16-channel electroencephalogram. Main variables were absolute alpha, theta, and delta amplitudes in frontal, temporal, and posterior regions.Results: There were no significant differences between the AN patients and controls regarding absolute regional band amplitudes in µV. Borderline significance was found for anterior theta (P=0.051). Significantly increased left and right frontal electrode theta amplitude was found in AN patients (F3, P=0.014; F4, P=0.038) compared to controls. Significant differences were also observed for secondary variables: lower values for relative parietooccipital delta and frontocentral alpha activity among AN patients than among controls.Conclusion: We observed slight excess frontal theta and lower relative alpha and delta amplitudes among AN patients than among controls. This pattern is possibly related to a slight frontal lobe dysfunction in AN, or it may reflect increased attention/vigilance or another state-related change in patients with AN compared to healthy controls. Keywords: anorexia, EEG, frontal theta, alpha, delta, eating disorders |
topic |
Anorexia EEG qEEG frontal theta alpha delta. |
url |
https://www.dovepress.com/increased-frontal-electroencephalogram-theta-amplitude-in-patients-wit-peer-reviewed-article-NDT |
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