Necrotizing Fasciitis Following Herpes Zoster Ophthalmicus in an Immunocompromised Patient
Necrotizing fasciitis (NF) is a rare infection that spreads rapidly along the subcutaneous soft tissue planes. NF rarely involves the periorbital region due to the excellent blood supply of this region. We report a case of periorbital necrotising fasciitis following herpes zoster (HZ) in an immunoco...
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Series: | Case Reports in Ophthalmological Medicine |
Online Access: | http://dx.doi.org/10.1155/2019/4534153 |
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doaj-7425ad5e33ab4c06871acfb2618521862020-11-24T22:08:36ZengHindawi LimitedCase Reports in Ophthalmological Medicine2090-67222090-67302019-01-01201910.1155/2019/45341534534153Necrotizing Fasciitis Following Herpes Zoster Ophthalmicus in an Immunocompromised PatientGrazia Maria Cozzupoli0Daniele Gui1Valerio Cozza2Claudio Lodoli3Mariano Alberto Pennisi4Aldo Caporossi5Benedetto Falsini6Fondazione Policlinico Universitario A. Gemelli, Università Cattolica del S. Cuore, Rome, ItalyFondazione Policlinico Universitario A. Gemelli, Università Cattolica del S. Cuore, Rome, ItalyFondazione Policlinico Universitario A. Gemelli, Università Cattolica del S. Cuore, Rome, ItalyFondazione Policlinico Universitario A. Gemelli, Università Cattolica del S. Cuore, Rome, ItalyFondazione Policlinico Universitario A. Gemelli, Università Cattolica del S. Cuore, Rome, ItalyFondazione Policlinico Universitario A. Gemelli, Università Cattolica del S. Cuore, Rome, ItalyFondazione Policlinico Universitario A. Gemelli, Università Cattolica del S. Cuore, Rome, ItalyNecrotizing fasciitis (NF) is a rare infection that spreads rapidly along the subcutaneous soft tissue planes. NF rarely involves the periorbital region due to the excellent blood supply of this region. We report a case of periorbital necrotising fasciitis following herpes zoster (HZ) in an immunocompromised 70-year-old patient with a dramatically rapid evolution into septic shock. In our patient, the surprisingly rapid spread of the bacterial superinfection led the periorbital cellulitis to turn into frank NF within 2 hours, with an overwhelming evolution. Despite the prompt start of a systemic antibiotic therapy and the immediate surgical intervention, the patient had a septic shock; she was treated in ITU for 31 days and then discharged to a medical ward and eventually died for a mix of complications of the medical treatment and comorbidities. This case is unique because any documented cases of periorbital NF triggered by HZ had never led to a septic shock and death. Ophthalmologists should be aware that even common skin lesions caused by shingles can determine a dramatic clinical picture, in presence of predisposing factors.http://dx.doi.org/10.1155/2019/4534153 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Grazia Maria Cozzupoli Daniele Gui Valerio Cozza Claudio Lodoli Mariano Alberto Pennisi Aldo Caporossi Benedetto Falsini |
spellingShingle |
Grazia Maria Cozzupoli Daniele Gui Valerio Cozza Claudio Lodoli Mariano Alberto Pennisi Aldo Caporossi Benedetto Falsini Necrotizing Fasciitis Following Herpes Zoster Ophthalmicus in an Immunocompromised Patient Case Reports in Ophthalmological Medicine |
author_facet |
Grazia Maria Cozzupoli Daniele Gui Valerio Cozza Claudio Lodoli Mariano Alberto Pennisi Aldo Caporossi Benedetto Falsini |
author_sort |
Grazia Maria Cozzupoli |
title |
Necrotizing Fasciitis Following Herpes Zoster Ophthalmicus in an Immunocompromised Patient |
title_short |
Necrotizing Fasciitis Following Herpes Zoster Ophthalmicus in an Immunocompromised Patient |
title_full |
Necrotizing Fasciitis Following Herpes Zoster Ophthalmicus in an Immunocompromised Patient |
title_fullStr |
Necrotizing Fasciitis Following Herpes Zoster Ophthalmicus in an Immunocompromised Patient |
title_full_unstemmed |
Necrotizing Fasciitis Following Herpes Zoster Ophthalmicus in an Immunocompromised Patient |
title_sort |
necrotizing fasciitis following herpes zoster ophthalmicus in an immunocompromised patient |
publisher |
Hindawi Limited |
series |
Case Reports in Ophthalmological Medicine |
issn |
2090-6722 2090-6730 |
publishDate |
2019-01-01 |
description |
Necrotizing fasciitis (NF) is a rare infection that spreads rapidly along the subcutaneous soft tissue planes. NF rarely involves the periorbital region due to the excellent blood supply of this region. We report a case of periorbital necrotising fasciitis following herpes zoster (HZ) in an immunocompromised 70-year-old patient with a dramatically rapid evolution into septic shock. In our patient, the surprisingly rapid spread of the bacterial superinfection led the periorbital cellulitis to turn into frank NF within 2 hours, with an overwhelming evolution. Despite the prompt start of a systemic antibiotic therapy and the immediate surgical intervention, the patient had a septic shock; she was treated in ITU for 31 days and then discharged to a medical ward and eventually died for a mix of complications of the medical treatment and comorbidities. This case is unique because any documented cases of periorbital NF triggered by HZ had never led to a septic shock and death. Ophthalmologists should be aware that even common skin lesions caused by shingles can determine a dramatic clinical picture, in presence of predisposing factors. |
url |
http://dx.doi.org/10.1155/2019/4534153 |
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