Aluminum chloride effect on Ca(2+),Mg(2+)-ATPase activity and dynamic parameters of skeletal muscle contraction
We studied enzymatic activity and measured strain-gauge contraction properties of the frog Rana temporaria m. tibialis anterior muscle fascicles during the action of aluminum chloride solution. It was shown that AlCl3 solutions did not affect the dynamic properties of skeletal muscle preparation in...
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National Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine.
2015-10-01
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| Series: | Ukrainian Biochemical Journal |
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| Online Access: | http://ukrbiochemjournal.org/wp-content/uploads/2015/10/Nozdrenko_5_15.pdf |
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doaj-7447e78469e5470ba45d71569b4ae69f2020-11-24T21:00:17ZengNational Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine.Ukrainian Biochemical Journal2409-49432413-50032015-10-01875384510.15407/ubj87.05.038Aluminum chloride effect on Ca(2+),Mg(2+)-ATPase activity and dynamic parameters of skeletal muscle contractionD. M. Nozdrenko0 O. M. Abramchuk1V. M. Soroca2N. S. Miroshnichenko3Lesya Ukrainka Eastern European National University, Lutsk, Ukraine;Lesya Ukrainka Eastern European National University, Lutsk, Ukraine;Lesya Ukrainka Eastern European National University, Lutsk, Ukraine;Lesya Ukrainka Eastern European National University, Lutsk, Ukraine;We studied enzymatic activity and measured strain-gauge contraction properties of the frog Rana temporaria m. tibialis anterior muscle fascicles during the action of aluminum chloride solution. It was shown that AlCl3 solutions did not affect the dynamic properties of skeletal muscle preparation in concentrations less than 10-4 M. Increasing the concentration of AlCl3 to 10-2 M induce complete inhibition of muscle contraction. A linear correlation between decrease in Ca2+,Mg2+-ATPase activity of sarcoplasmic reticulum and the investigated concentrations range of aluminum chloride was observed. The reduction in the dynamic contraction performance and the decrease Ca2+,Mg2+-ATPase activity of the sarcoplasmic reticulum under the effect of the investigated AlCl3 solution were minimal in pre-tetanus period of contraction.http://ukrbiochemjournal.org/wp-content/uploads/2015/10/Nozdrenko_5_15.pdfaluminum chlorideCa(2+)-Mg(2+)-ATPase activitylength of muscle fibersmuscle contractile forcemuscle contraction |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
D. M. Nozdrenko O. M. Abramchuk V. M. Soroca N. S. Miroshnichenko |
| spellingShingle |
D. M. Nozdrenko O. M. Abramchuk V. M. Soroca N. S. Miroshnichenko Aluminum chloride effect on Ca(2+),Mg(2+)-ATPase activity and dynamic parameters of skeletal muscle contraction Ukrainian Biochemical Journal aluminum chloride Ca(2+)-Mg(2+)-ATPase activity length of muscle fibers muscle contractile force muscle contraction |
| author_facet |
D. M. Nozdrenko O. M. Abramchuk V. M. Soroca N. S. Miroshnichenko |
| author_sort |
D. M. Nozdrenko |
| title |
Aluminum chloride effect on Ca(2+),Mg(2+)-ATPase activity and dynamic parameters of skeletal muscle contraction |
| title_short |
Aluminum chloride effect on Ca(2+),Mg(2+)-ATPase activity and dynamic parameters of skeletal muscle contraction |
| title_full |
Aluminum chloride effect on Ca(2+),Mg(2+)-ATPase activity and dynamic parameters of skeletal muscle contraction |
| title_fullStr |
Aluminum chloride effect on Ca(2+),Mg(2+)-ATPase activity and dynamic parameters of skeletal muscle contraction |
| title_full_unstemmed |
Aluminum chloride effect on Ca(2+),Mg(2+)-ATPase activity and dynamic parameters of skeletal muscle contraction |
| title_sort |
aluminum chloride effect on ca(2+),mg(2+)-atpase activity and dynamic parameters of skeletal muscle contraction |
| publisher |
National Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine. |
| series |
Ukrainian Biochemical Journal |
| issn |
2409-4943 2413-5003 |
| publishDate |
2015-10-01 |
| description |
We studied enzymatic activity and measured strain-gauge contraction properties of the frog Rana temporaria m. tibialis anterior muscle fascicles during the action of aluminum chloride solution. It was shown that AlCl3 solutions did not affect the dynamic properties of skeletal muscle preparation in concentrations less than 10-4 M. Increasing the concentration of AlCl3 to 10-2 M induce complete inhibition of muscle contraction. A linear correlation between decrease in Ca2+,Mg2+-ATPase activity of sarcoplasmic reticulum and the investigated concentrations range of aluminum chloride was observed. The reduction in the dynamic contraction performance and the decrease Ca2+,Mg2+-ATPase activity of the sarcoplasmic reticulum under the effect of the investigated AlCl3 solution were minimal in pre-tetanus period of contraction. |
| topic |
aluminum chloride Ca(2+)-Mg(2+)-ATPase activity length of muscle fibers muscle contractile force muscle contraction |
| url |
http://ukrbiochemjournal.org/wp-content/uploads/2015/10/Nozdrenko_5_15.pdf |
| work_keys_str_mv |
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