Cutaneous blastomycosis: a clue to a systemic disease Blastomicose cutânea: um sinal de doença sistêmica

• Main Authors: Alex G Ortega-Loayza, Tuyet Nguyen
• Format: Article
• Language: English
• Published: Sociedade Brasileira de Dermatologia 2013-04-01
• Series: Anais Brasileiros de Dermatologia
• Subjects: Blastomicose; Cromoblastomicose; Coccidioidomicose; Paracoccidioidomicose; Blastomycosis; Chromoblastomycosis; Coccidioidomycosis; Paracoccidioidomycosis
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000200287
• ISSN: 0365-0596; 1806-4841

A 55-year-old male presented with back pain and slightly tender annular plaques with central ulceration on his face. A skin biopsy revealed scattered yeast with broad based buds. A CT scan of the abdomen revealed a pathologic T12 fracture. Tissue obtained from the spine confirmed budding yeasts. The patient was diagnosed with disseminated blastomycosis. The patient was treated with amphotericin and itraconazole and completely recovered.<br>Paciente do sexo masculino, com 55 anos de idade, compareceu ao ambulat&#243;rio com dores na costa e placas anulares ligeiramente sens&#237;veis, com ulcera&#231;&#227;o central na face. Uma bi&#243;psia cut&#226;nea revelou levedura disseminada, com brotos de base larga. A tomografia computadorizada do abd&#244;men revelou uma fratura patol&#243;gica da T12. Amostra de tecido obtido da coluna vertebral confirmou levedura em fase de brotamento. O paciente foi diagnosticado com blastomicose disseminada. Ap&#243;s tratamento com anfotericina e itraconazol, o paciente teve recupera&#231;&#227;o completa.