SPS-neutralization in tissue samples for efficacy testing of antimicrobial peptides

SPS-neutralization in tissue samples for efficacy testing of antimicrobial peptides

Abstract Background Accurate determination of the efficacy of antimicrobial agents requires neutralization of residual antimicrobial activity in the samples before microbiological assessment of the number of surviving bacteria. Sodium polyanethol sulfonate (SPS) is a known neutralizer for the antimi...

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Bibliographic Details
Main Authors: Gabrielle Sherella Dijksteel, Peter H. Nibbering, Magda M. W. Ulrich, Esther Middelkoop, Bouke K. H. L. Boekema
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Infectious Diseases
Subjects:
Sodium polyanethol sulfonate
Antimicrobial peptides
SAAP-148
Efficacy
Residual activity
Neutralization
Online Access:https://doi.org/10.1186/s12879-019-4700-1

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