Mechanisms of Maintenance of Foot-and-Mouth Disease Virus Persistence Inferred From Genes Differentially Expressed in Nasopharyngeal Epithelia of Virus Carriers and Non-carriers

Mechanisms of Maintenance of Foot-and-Mouth Disease Virus Persistence Inferred From Genes Differentially Expressed in Nasopharyngeal Epithelia of Virus Carriers and Non-carriers

Foot-and-mouth disease virus (FMDV) causes persistent infection of nasopharyngeal epithelial cells in ~50% of infected ruminants. The mechanisms involved are not clear. This study provides a continued investigation of differentially expressed genes (DEG) identified in a previously published transcri...

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Bibliographic Details
Main Authors: James J. Zhu, Carolina Stenfeldt, Elizabeth A. Bishop, Jessica A. Canter, Michael Eschbaumer, Luis L. Rodriguez, Jonathan Arzt
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Veterinary Science
Subjects:
foot-and-mouth disease virus
FMDV
microarray analysis
persistent infection
pharyngeal epithelia
chemokine expression
Online Access:https://www.frontiersin.org/article/10.3389/fvets.2020.00340/full

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