Comparative study of endometrioid borderline ovarian tumor with and without endometriosis

• Main Authors: Wen Zhang, Shuangzheng Jia, Yang Xiang, Junjun Yang, Congwei Jia, Jinhua Leng
• Format: Article
• Language: English
• Published: BMC 2018-08-01
• Series: Journal of Ovarian Research
• Subjects: Endometrioid borderline ovarian tumor; Endometriosis-associated endometrioid borderline ovarian tumor; Endometriosis
• Online Access: http://link.springer.com/article/10.1186/s13048-018-0440-x

Abstract Background Synchronous endometriosis has been poorly studied in women with endometrioid borderline ovarian tumors (EBOTs). The aims of this study were to compare the clinicopathological features and prognosis of EBOTs with or without endometriosis. Results Of 52 patients diagnosed with EBOTs, no death was observed and only one case had successful pregnancy during the follow-up period. Older, menopausal EBOT patients, EBOT patients with small tumors and relatively low CA125 level probably had better progression-free survival (PFS) outcomes. About 1/3 of EBOTs had concomitant endometrial lesions. Approximately 1/3 of EBOTs were associated with endometriosis. Patients were divided into two groups according to the presence or not of endometriosis in this retrospective cohort study. Patients with endometriosis-associated endometrioid borderline ovarian tumor (EAEBOT) were more likely to be younger and premenopausal. Variables such as PFS outcomes, endometrial lesions did not differ statistically between groups. However, in specific EBOT patients like parous patients, patients with CA125 ≥ 140 U/ml or patients without fertility sparing surgery, coexisting endometriosis perhaps predicted worse PFS outcomes. Conclusion We considered EAEBOT as an entity similar to non-EAEBOT. Closely follow-up for some particular patients with concomitant endometriosis was necessary.