Role of peptidoglycan in the pathogenesis of Staphylococcus saprophyticus in mice

The pathogenicity of S. saprophyticus was studied in mice. A group of white mice were injected transurethrally using a catheter with S. saprophyticus S67 cell suspension in a concentration reached 109 CFU/ml. concomitantly, the role of its peptidoglycan in the pathogenicity was studied by injecting...

Full description

Bibliographic Details
Main Author: Baghdad Science Journal
Format: Article
Language:Arabic
Published: College of Science for Women, University of Baghdad 2007-12-01
Series:Baghdad Science Journal
Online Access:http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/841
id doaj-74ac286227524b048e11e63640ba4e80
record_format Article
spelling doaj-74ac286227524b048e11e63640ba4e802020-11-25T00:12:56ZaraCollege of Science for Women, University of BaghdadBaghdad Science Journal2078-86652411-79862007-12-014410.21123/bsj.4.4.597-602Role of peptidoglycan in the pathogenesis of Staphylococcus saprophyticus in miceBaghdad Science JournalThe pathogenicity of S. saprophyticus was studied in mice. A group of white mice were injected transurethrally using a catheter with S. saprophyticus S67 cell suspension in a concentration reached 109 CFU/ml. concomitantly, the role of its peptidoglycan in the pathogenicity was studied by injecting another group of mice with 0.3 mg/0.2 ml of partially purified S. saprophyticus S67 peptidoglycan extract. After autopsy, kidneys and urinary bladder showed several histopathological changes both in cells and peptidoglycan injected mice, included: hydropic degeneration, glomerulus shrinkage, congestion of renal vessels, infiltration of inflammatory cells, and dekeratinization in urinary bladder.http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/841
collection DOAJ
language Arabic
format Article
sources DOAJ
author Baghdad Science Journal
spellingShingle Baghdad Science Journal
Role of peptidoglycan in the pathogenesis of Staphylococcus saprophyticus in mice
Baghdad Science Journal
author_facet Baghdad Science Journal
author_sort Baghdad Science Journal
title Role of peptidoglycan in the pathogenesis of Staphylococcus saprophyticus in mice
title_short Role of peptidoglycan in the pathogenesis of Staphylococcus saprophyticus in mice
title_full Role of peptidoglycan in the pathogenesis of Staphylococcus saprophyticus in mice
title_fullStr Role of peptidoglycan in the pathogenesis of Staphylococcus saprophyticus in mice
title_full_unstemmed Role of peptidoglycan in the pathogenesis of Staphylococcus saprophyticus in mice
title_sort role of peptidoglycan in the pathogenesis of staphylococcus saprophyticus in mice
publisher College of Science for Women, University of Baghdad
series Baghdad Science Journal
issn 2078-8665
2411-7986
publishDate 2007-12-01
description The pathogenicity of S. saprophyticus was studied in mice. A group of white mice were injected transurethrally using a catheter with S. saprophyticus S67 cell suspension in a concentration reached 109 CFU/ml. concomitantly, the role of its peptidoglycan in the pathogenicity was studied by injecting another group of mice with 0.3 mg/0.2 ml of partially purified S. saprophyticus S67 peptidoglycan extract. After autopsy, kidneys and urinary bladder showed several histopathological changes both in cells and peptidoglycan injected mice, included: hydropic degeneration, glomerulus shrinkage, congestion of renal vessels, infiltration of inflammatory cells, and dekeratinization in urinary bladder.
url http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/841
work_keys_str_mv AT baghdadsciencejournal roleofpeptidoglycaninthepathogenesisofstaphylococcussaprophyticusinmice
_version_ 1725396620644712448