The role of emollients in pathogenetic therapy of atopic dermatitis in children
Atopic dermatitis (AtD) is the most common inflammatory skin disease in childhood. In practical healthcare, the basic mechanism for the development of AtD in children is food allergy. However, recent studies demonstrate that disruptions of the skin barrier structure play a relevant role in the patho...
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| Format: | Article |
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Remedium Group LLC
2017-12-01
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| Series: | Медицинский совет |
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| Online Access: | https://www.med-sovet.pro/jour/article/view/1677 |
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doaj-74caba197efb4fce8353db5b772949ea2021-07-28T13:29:32ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902017-12-0101455010.21518/2079-701X-2017-1-45-501664The role of emollients in pathogenetic therapy of atopic dermatitis in childrenS. V. Zaytseva0Moscow State University of Medicine and Dentistry named after A.I. EvdokimovAtopic dermatitis (AtD) is the most common inflammatory skin disease in childhood. In practical healthcare, the basic mechanism for the development of AtD in children is food allergy. However, recent studies demonstrate that disruptions of the skin barrier structure play a relevant role in the pathogenesis of AtD, contributing to xeroderma and increased skin permeability to allergens. Accordingly, AtD therapy should be targeted not only at relief of allergic reactions but also at restoration and maintenance of the skin barrier integrity. The key role here belongs to agents that restore epidermal lipid content – emollients. Among representatives of the group of treatments, the effectiveness of Stelatopia moisturizing emulsion for the treatment of atopic dermatitis in children was confirmed by clinical trials.https://www.med-sovet.pro/jour/article/view/1677atopic dermatitisskin barrieremollientsstelatopia |
| collection |
DOAJ |
| language |
Russian |
| format |
Article |
| sources |
DOAJ |
| author |
S. V. Zaytseva |
| spellingShingle |
S. V. Zaytseva The role of emollients in pathogenetic therapy of atopic dermatitis in children Медицинский совет atopic dermatitis skin barrier emollients stelatopia |
| author_facet |
S. V. Zaytseva |
| author_sort |
S. V. Zaytseva |
| title |
The role of emollients in pathogenetic therapy of atopic dermatitis in children |
| title_short |
The role of emollients in pathogenetic therapy of atopic dermatitis in children |
| title_full |
The role of emollients in pathogenetic therapy of atopic dermatitis in children |
| title_fullStr |
The role of emollients in pathogenetic therapy of atopic dermatitis in children |
| title_full_unstemmed |
The role of emollients in pathogenetic therapy of atopic dermatitis in children |
| title_sort |
role of emollients in pathogenetic therapy of atopic dermatitis in children |
| publisher |
Remedium Group LLC |
| series |
Медицинский совет |
| issn |
2079-701X 2658-5790 |
| publishDate |
2017-12-01 |
| description |
Atopic dermatitis (AtD) is the most common inflammatory skin disease in childhood. In practical healthcare, the basic mechanism for the development of AtD in children is food allergy. However, recent studies demonstrate that disruptions of the skin barrier structure play a relevant role in the pathogenesis of AtD, contributing to xeroderma and increased skin permeability to allergens. Accordingly, AtD therapy should be targeted not only at relief of allergic reactions but also at restoration and maintenance of the skin barrier integrity. The key role here belongs to agents that restore epidermal lipid content – emollients. Among representatives of the group of treatments, the effectiveness of Stelatopia moisturizing emulsion for the treatment of atopic dermatitis in children was confirmed by clinical trials. |
| topic |
atopic dermatitis skin barrier emollients stelatopia |
| url |
https://www.med-sovet.pro/jour/article/view/1677 |
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AT svzaytseva theroleofemollientsinpathogenetictherapyofatopicdermatitisinchildren AT svzaytseva roleofemollientsinpathogenetictherapyofatopicdermatitisinchildren |
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