Label-Free Protein-RNA Interactome Analysis Identifies Khsrp Signaling Downstream of the p38/Mk2 Kinase Complex as a Critical Modulator of Cell Cycle Progression.
Growing evidence suggests a key role for RNA binding proteins (RBPs) in genome stability programs. Additionally, recent developments in RNA sequencing technologies, as well as mass-spectrometry techniques, have greatly expanded our knowledge on protein-RNA interactions. We here use full transcriptom...
Main Authors: | Jorge Boucas, Christian Fritz, Anna Schmitt, Arina Riabinska, Lisa Thelen, Martin Peifer, Uschi Leeser, Peter Nuernberg, Janine Altmueller, Matthias Gaestel, Christoph Dieterich, H Christian Reinhardt |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0125745 |
Similar Items
-
The p38/MK2 Axis in Monocytes of Fibromyalgia Syndrome Patients: An Explorative Study
by: Boya Nugraha, et al.
Published: (2021-04-01) -
The p38/MK2-driven exchange between tristetraprolin and HuR regulates AU-rich element-dependent translation.
by: Christopher Tiedje, et al.
Published: (2012-09-01) -
RNA-binding protein KHSRP promotes tumor growth and metastasis in non-small cell lung cancer
by: Mingxia Yan, et al.
Published: (2019-11-01) -
SUMO1 modification of KHSRP regulates tumorigenesis by preventing the TL-G-Rich miRNA biogenesis
by: Haihua Yuan, et al.
Published: (2017-10-01) -
KHSRP loss increases neuronal growth and synaptic transmission and alters memory consolidation through RNA stabilization
by: Allan, A.M, et al.
Published: (2022)