Application of palladium-mediated (18)F-fluorination to PET radiotracer development: overcoming hurdles to translation.

Application of palladium-mediated (18)F-fluorination to PET radiotracer development: overcoming hurdles to translation.

New chemistry methods for the synthesis of radiolabeled small molecules have the potential to impact clinical positron emission tomography (PET) imaging, if they can be successfully translated. However, progression of modern reactions from the stage of synthetic chemistry development to the preparat...

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Bibliographic Details
Main Authors: Adam S Kamlet, Constanze N Neumann, Eunsung Lee, Stephen M Carlin, Christian K Moseley, Nickeisha Stephenson, Jacob M Hooker, Tobias Ritter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3595243?pdf=render

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http://europepmc.org/articles/PMC3595243?pdf=render

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