Evaluation of safety and immunogenicity of a group A streptococcus vaccine candidate (MJ8VAX) in a randomized clinical trial.

BACKGROUND:Group A streptococcus (GAS) is a serious human pathogen that affects people of different ages and socio-economic levels. Although vaccination is potentially one of the most effective methods to control GAS infection and its sequelae, few prototype vaccines have been investigated in humans...

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Main Authors: Silvana Sekuloski, Michael R Batzloff, Paul Griffin, William Parsonage, Suzanne Elliott, Jon Hartas, Peter O'Rourke, Louise Marquart, Manisha Pandey, Fran A Rubin, Jonathan Carapetis, James McCarthy, Michael F Good
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6028081?pdf=render