APOE and MAPT Are Associated With Dementia in Neuropathologically Confirmed Parkinson's Disease

APOE and MAPT Are Associated With Dementia in Neuropathologically Confirmed Parkinson's Disease

Introduction: Cognitive decline and dementia are common and debilitating non-motor phenotypic features of Parkinson's disease with a variable severity and time of onset. Common genetic variation of the Apolipoprotein E (APOE) and micro-tubule associated protein tau (MAPT) loci have been linked...

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Bibliographic Details
Main Authors: Jon-Anders Tunold, Hanneke Geut, J. M. Annemieke Rozemuller, Sandra Pilar Henriksen, Mathias Toft, Wilma D. J. van de Berg, Lasse Pihlstrøm
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Neurology
Subjects:
parkinson's disease
dementia
neuropathology
genetics
association study
APOE
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.631145/full

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