Elevated serum ferritin is associated with reduced survival in amyotrophic lateral sclerosis.

Elevated serum ferritin is associated with reduced survival in amyotrophic lateral sclerosis.

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder caused by the loss of motor neurons. Its etiology remains unknown, but several hypothesis have been raised to explain motor neuron death, including oxidative stress. Dysregulation of cellular iron metabolism can lead to...

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Bibliographic Details
Main Authors: Yann Nadjar, Paul Gordon, Philippe Corcia, Gilbert Bensimon, Laurence Pieroni, Vincent Meininger, François Salachas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3443244?pdf=render

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