Host immune cellular reactions in corneal neovascularization

Corneal neovascularization (CNV) is a global important cause of visual impairment. The immune mechanisms leading to corneal heme- and lymphangiogenesis have been extensively studied over the past years as more attempts were made to develop better prophylactic and therapeutic measures. This article a...

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Bibliographic Details
Main Authors: Nizar S. Abdelfattah, Mohamed Amgad, Amira A Zayed
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2016-04-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.cn/en_publish/2016/4/20160425.pdf
Description
Summary:Corneal neovascularization (CNV) is a global important cause of visual impairment. The immune mechanisms leading to corneal heme- and lymphangiogenesis have been extensively studied over the past years as more attempts were made to develop better prophylactic and therapeutic measures. This article aims to discuss immune cells of particular relevance to CNV, with a focus on macrophages, Th17 cells, dendritic cells and the underlying immunology of common pathologies involving neovascularization of the cornea. Hopefully, a thorough understanding of these topics would propel the efforts to halt the detrimental effects of CNV.
ISSN:2222-3959
2227-4898