Regulation of sphingolipid and glycosphingolipid metabolism in extrahepatic tissues by endotoxin

Regulation of sphingolipid and glycosphingolipid metabolism in extrahepatic tissues by endotoxin

The host response to infection and inflammation is associated with multiple alterations in lipid metabolism. We have shown that endotoxin [lipopolysaccharide (LPS)] stimulates hepatic sphingolipid synthesis and increases ceramide and glucosylceramide (GlcCer) content in circulating lipoproteins in S...

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Bibliographic Details
Main Authors:	Riaz A. Memon, Walter M. Holleran, Yoshikazu Uchida, Arthur H. Moser, Carl Grunfeld, Kenneth R. Feingold
Format:	Article
Language:	English
Published:	Elsevier 2001-03-01
Series:	Journal of Lipid Research
Subjects:	serine palmitoyltransferase glucosylceramide synthase acute-phase response spleen kidney
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520316709

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