Evaluation of Tear Film Osmolarity in Cases with Chronic Blepharitis
Objectives: To investigate the tear film osmolarity in eyes with chronic blepharitis. Materials and Methods: Patients with symptomatic chronic blepharitis were included in the study. After ophthalmologic examination, tear osmolarity was measured. Tear film breakup time (TBUT), Schirmer II test wit...
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Galenos Yayinevi
2015-01-01
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Series: | Türk Oftalmoloji Dergisi |
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Online Access: | http://www.oftalmoloji.org/article_8653/Evaluation-Of-Tear-Film-Osmolarity-In-Cases-With-Chronic-Blepharitis |
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doaj-7537e08bb69d4ba0bbc60a64454186012020-11-24T23:40:21ZengGalenos YayineviTürk Oftalmoloji Dergisi1300-06592147-26612015-01-014515810.4274/tjo.73792Evaluation of Tear Film Osmolarity in Cases with Chronic BlepharitisRaciha Beril Küçümen0Canan Aslı Utine1 Ebru Görgün2 Nursal Melda Yenerel3Şule Ziylan4Ferda Çiftçi5Yeditepe Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, İstanbul, TürkiyeYeditepe Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, İstanbul, TürkiyeDünya Göz Hastanesi, Göz Hastalıkları Kliniği, İstanbul, TürkiyeHaydarpaşa Eğitim ve Araştırma Hastanesi, Göz Hastalıkları Kliniği, İstanbul, TürkiyeYeditepe Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, İstanbul, TürkiyeYeditepe Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, İstanbul, TürkiyeObjectives: To investigate the tear film osmolarity in eyes with chronic blepharitis. Materials and Methods: Patients with symptomatic chronic blepharitis were included in the study. After ophthalmologic examination, tear osmolarity was measured. Tear film breakup time (TBUT), Schirmer II test with anesthesia, and slit-lamp corneal fluorescein staining were also performed. The tear film osmolarity results were compared with those of healthy subjects. Results: Ten eyes of 10 patients (6 women, 2 men) with a mean age of 47.4±14.4 years (31 to 62 years) and 12 eyes of 12 healthy individuals (10 women, 2 men) were examined. Patients’ symptoms included foreign body sensation, photophobia, redness, burning, itching, scaling, eyelash loss, and recurrent hordeolum. There was no any other systemic or ocular pathology that could result in dry eye. Mean osmolarity was 323.8±19.91 mOsm/L (298-365 mOsm/L), mean TBUT was 4.22±2.17 seconds (1-8 secs,), and mean Schirmer measurement was 7.2±3.26 mm (4-15 mm). Corneal staining was observed in 65% of the eyes. The mean osmolarity of normal group was 302.17±8.54 mOsm/L (288-316 mOsm/L), mean TBUT was 12.5±4.52 seconds (8-23 secs), and mean Schirmer measurement was 13.17±7.83 mm (5-30 mm). There was a statistically significant difference between the mean osmolarity, TBUT, and Schirmer measurements of the two groups (t-test; p=0.003, p<0.001, and p=0.04, respectively). Conclusion: The dry eye symptoms in chronic blepharitis result from imbalance between the aqueous and lipid components of the tear film allowing increased evaporation. This condition does not only change TBUT and Schirmer results but also increases the osmolarity of the tear film significantly indicating serious dry eye disease in chronic blepharitis. (Turk J Ophthalmol 2015; 45: 5-8)http://www.oftalmoloji.org/article_8653/Evaluation-Of-Tear-Film-Osmolarity-In-Cases-With-Chronic-BlepharitisBlepharitistear film osmolaritydry eye |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Raciha Beril Küçümen Canan Aslı Utine Ebru Görgün Nursal Melda Yenerel Şule Ziylan Ferda Çiftçi |
spellingShingle |
Raciha Beril Küçümen Canan Aslı Utine Ebru Görgün Nursal Melda Yenerel Şule Ziylan Ferda Çiftçi Evaluation of Tear Film Osmolarity in Cases with Chronic Blepharitis Türk Oftalmoloji Dergisi Blepharitis tear film osmolarity dry eye |
author_facet |
Raciha Beril Küçümen Canan Aslı Utine Ebru Görgün Nursal Melda Yenerel Şule Ziylan Ferda Çiftçi |
author_sort |
Raciha Beril Küçümen |
title |
Evaluation of Tear Film Osmolarity in Cases with Chronic Blepharitis |
title_short |
Evaluation of Tear Film Osmolarity in Cases with Chronic Blepharitis |
title_full |
Evaluation of Tear Film Osmolarity in Cases with Chronic Blepharitis |
title_fullStr |
Evaluation of Tear Film Osmolarity in Cases with Chronic Blepharitis |
title_full_unstemmed |
Evaluation of Tear Film Osmolarity in Cases with Chronic Blepharitis |
title_sort |
evaluation of tear film osmolarity in cases with chronic blepharitis |
publisher |
Galenos Yayinevi |
series |
Türk Oftalmoloji Dergisi |
issn |
1300-0659 2147-2661 |
publishDate |
2015-01-01 |
description |
Objectives: To investigate the tear film osmolarity in eyes with chronic blepharitis.
Materials and Methods: Patients with symptomatic chronic blepharitis were included in the study. After ophthalmologic examination,
tear osmolarity was measured. Tear film breakup time (TBUT), Schirmer II test with anesthesia, and slit-lamp corneal fluorescein staining
were also performed. The tear film osmolarity results were compared with those of healthy subjects.
Results: Ten eyes of 10 patients (6 women, 2 men) with a mean age of 47.4±14.4 years (31 to 62 years) and 12 eyes of 12 healthy
individuals (10 women, 2 men) were examined. Patients’ symptoms included foreign body sensation, photophobia, redness, burning,
itching, scaling, eyelash loss, and recurrent hordeolum. There was no any other systemic or ocular pathology that could result in dry eye.
Mean osmolarity was 323.8±19.91 mOsm/L (298-365 mOsm/L), mean TBUT was 4.22±2.17 seconds (1-8 secs,), and mean Schirmer
measurement was 7.2±3.26 mm (4-15 mm). Corneal staining was observed in 65% of the eyes. The mean osmolarity of normal group
was 302.17±8.54 mOsm/L (288-316 mOsm/L), mean TBUT was 12.5±4.52 seconds (8-23 secs), and mean Schirmer measurement
was 13.17±7.83 mm (5-30 mm). There was a statistically significant difference between the mean osmolarity, TBUT, and Schirmer
measurements of the two groups (t-test; p=0.003, p<0.001, and p=0.04, respectively).
Conclusion: The dry eye symptoms in chronic blepharitis result from imbalance between the aqueous and lipid components of the tear
film allowing increased evaporation. This condition does not only change TBUT and Schirmer results but also increases the osmolarity
of the tear film significantly indicating serious dry eye disease in chronic blepharitis. (Turk J Ophthalmol 2015; 45: 5-8) |
topic |
Blepharitis tear film osmolarity dry eye |
url |
http://www.oftalmoloji.org/article_8653/Evaluation-Of-Tear-Film-Osmolarity-In-Cases-With-Chronic-Blepharitis |
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