Circadian disruption accelerates tumor growth and angio/stromagenesis through a Wnt signaling pathway.

Circadian disruption accelerates tumor growth and angio/stromagenesis through a Wnt signaling pathway.

Epidemiologic studies show a high incidence of cancer in shift workers, suggesting a possible relationship between circadian rhythms and tumorigenesis. However, the precise molecular mechanism played by circadian rhythms in tumor progression is not known. To identify the possible mechanisms underlyi...

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Bibliographic Details
Main Authors: Yoshihiro Yasuniwa, Hiroto Izumi, Ke-Yong Wang, Shohei Shimajiri, Yasuyuki Sasaguri, Kazuaki Kawai, Hiroshi Kasai, Takashi Shimada, Koichi Miyake, Eiji Kashiwagi, Gen Hirano, Akihiko Kidani, Masaki Akiyama, Bin Han, Ying Wu, Ichiro Ieiri, Shun Higuchi, Kimitoshi Kohno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3009728?pdf=render

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http://europepmc.org/articles/PMC3009728?pdf=render

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