Impact of Fixed Orthodontic Appliance with Diabetes Mellitus and Curcumin on the Body Weight of Experimental Rat
Background: This study aims to investigate the effect of diabetes mellitus, fixed orthodontic appliance and curcumin on the weight of experimental rats. Materials and Methods: Orthodontic tooth movement (OTM) take place in one side of a 'Split- mouth design study in 40 male Wistar albino rat...
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doaj-754c0d0a09444f8dacc0541076a3e5162020-11-25T02:51:53ZengAmber PublicationJournal of Research in Medical and Dental Science2347-25452347-23672020-04-01824248Impact of Fixed Orthodontic Appliance with Diabetes Mellitus and Curcumin on the Body Weight of Experimental RatZahra Kased Hussein0Hayder Fadhil Saloom1Department of Orthodontic, College of Dentistry, University of Baghdad, IraqDepartment of Orthodontic, College of Dentistry, University of Baghdad, IraqBackground: This study aims to investigate the effect of diabetes mellitus, fixed orthodontic appliance and curcumin on the weight of experimental rats. Materials and Methods: Orthodontic tooth movement (OTM) take place in one side of a 'Split- mouth design study in 40 male Wistar albino rats, divided into four groups: non-diabetic group (n=10), non-diabetic and curcumin group (n=10), induced diabetes group (n=10) and induced diabetes and curcumin group (n=10). Diabetes type1 was induced and insulin was given throughout the experiments for controlling high blood glucose levels. Fixed orthodontic appliance with a closing-coil spring delivering 30 gm of force was used to move the first molar mesially while the incisors serving as an anchor unit. The weight of the animals was measured once a week till the day of scarifying the animal after 3weeks. Results: the results showed that all groups suffered from an intense weight loss during the third week and concluded that fixed orthodontic appliance, diabetes mellitus and curcumin can be considered as causative factors. Conclusion: the study concluded that diabetes mellitus, orthodontic treatment and curcumin cause reduction of body weight in rats.https://www.jrmds.in/articles/impact-of-fixed-orthodontic-appliance-with-diabetes-mellitus-and-curcumin-on-the-body-weight-of-experimental-rat.pdfcurcuminratfixed orthodontic appliancediabetes mellitusweight |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Zahra Kased Hussein Hayder Fadhil Saloom |
spellingShingle |
Zahra Kased Hussein Hayder Fadhil Saloom Impact of Fixed Orthodontic Appliance with Diabetes Mellitus and Curcumin on the Body Weight of Experimental Rat Journal of Research in Medical and Dental Science curcumin rat fixed orthodontic appliance diabetes mellitus weight |
author_facet |
Zahra Kased Hussein Hayder Fadhil Saloom |
author_sort |
Zahra Kased Hussein |
title |
Impact of Fixed Orthodontic Appliance with Diabetes Mellitus and Curcumin on the Body Weight of Experimental Rat |
title_short |
Impact of Fixed Orthodontic Appliance with Diabetes Mellitus and Curcumin on the Body Weight of Experimental Rat |
title_full |
Impact of Fixed Orthodontic Appliance with Diabetes Mellitus and Curcumin on the Body Weight of Experimental Rat |
title_fullStr |
Impact of Fixed Orthodontic Appliance with Diabetes Mellitus and Curcumin on the Body Weight of Experimental Rat |
title_full_unstemmed |
Impact of Fixed Orthodontic Appliance with Diabetes Mellitus and Curcumin on the Body Weight of Experimental Rat |
title_sort |
impact of fixed orthodontic appliance with diabetes mellitus and curcumin on the body weight of experimental rat |
publisher |
Amber Publication |
series |
Journal of Research in Medical and Dental Science |
issn |
2347-2545 2347-2367 |
publishDate |
2020-04-01 |
description |
Background: This study aims to investigate the effect of diabetes mellitus, fixed orthodontic appliance and curcumin on the weight of experimental rats.
Materials and Methods: Orthodontic tooth movement (OTM) take place in one side of a 'Split- mouth design study in 40 male Wistar albino rats, divided into four groups: non-diabetic group (n=10), non-diabetic and curcumin group (n=10), induced diabetes group (n=10) and induced diabetes and curcumin group (n=10). Diabetes type1 was induced and insulin was given throughout the experiments for controlling high blood glucose levels. Fixed orthodontic appliance with a closing-coil spring delivering 30 gm of force was used to move the first molar mesially while the incisors serving as an anchor unit. The weight of the animals was measured once a week till the day of scarifying the animal after 3weeks.
Results: the results showed that all groups suffered from an intense weight loss during the third week and concluded that fixed orthodontic appliance, diabetes mellitus and curcumin can be considered as causative factors. Conclusion: the study concluded that diabetes mellitus, orthodontic treatment and curcumin cause reduction of body weight in rats. |
topic |
curcumin rat fixed orthodontic appliance diabetes mellitus weight |
url |
https://www.jrmds.in/articles/impact-of-fixed-orthodontic-appliance-with-diabetes-mellitus-and-curcumin-on-the-body-weight-of-experimental-rat.pdf |
work_keys_str_mv |
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