Pain without Nociceptors? Nav1.7-Independent Pain Mechanisms

Pain without Nociceptors? Nav1.7-Independent Pain Mechanisms

Nav1.7, a peripheral neuron voltage-gated sodium channel, is essential for pain and olfaction in mice and humans. We examined the role of Nav1.7 as well as Nav1.3, Nav1.8, and Nav1.9 in different mouse models of chronic pain. Constriction-injury-dependent neuropathic pain is abolished when Nav1.7 is...

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Bibliographic Details
Main Authors:	Michael S. Minett, Sarah Falk, Sonia Santana-Varela, Yury D. Bogdanov, Mohammed A. Nassar, Anne-Marie Heegaard, John N. Wood
Format:	Article
Language:	English
Published:	Elsevier 2014-01-01
Series:	Cell Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124713007912

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