Identification and validation of prognosis‐related DLX5 methylation as an epigenetic driver in myeloid neoplasms

Identification and validation of prognosis‐related DLX5 methylation as an epigenetic driver in myeloid neoplasms

Abstract The deregulated DLX gene family members DLX1/2/3/4/5/6 (DLXs) caused by DNA methylation has been demonstrated in various cancers with therapeutic target value. However, the potential role of DLXs methylation in myeloid neoplasms such as acute myeloid leukemia (AML) and myelodysplastic syndr...

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Bibliographic Details
Main Authors: Ting‐juan Zhang, Zi‐jun Xu, Yu Gu, Xiang‐mei Wen, Ji‐chun Ma, Wei Zhang, Zhao‐qun Deng, Jia‐yan Leng, Jun Qian, Jiang Lin, Jing‐dong Zhou
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Clinical and Translational Medicine
Subjects:
AML
DLX5
MDS
methylation
progression
Online Access:https://doi.org/10.1002/ctm2.29

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