High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: <it>KRAS </it>codon 12 and 13 mutations in non-small cell lung cancer

<p>Abstract</p> <p>Background</p> <p>The development of targeted therapies has created a pressing clinical need for the rapid and robust molecular characterisation of cancers. We describe here the application of high-resolution melting analysis (HRM) to screen for <i...

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Bibliographic Details
Main Authors: Thomas David M, Newnham Genni M, Krypuy Michael, Conron Matthew, Dobrovic Alexander
Format: Article
Language:English
Published: BMC 2006-12-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/6/295

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